Detailed information NTG1138427

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL29_RS06760
• Genome accession: NZ_LS483359
• Coordinates: 1339907..1340632 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12068
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1334907..1345632

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL29_RS06725 (NCTC12068_01333)	rnpM	1334941..1335237 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQL29_RS06730 (NCTC12068_01334)	nusA	1335253..1336410 (-)	1158	WP_023611711.1	transcription termination factor NusA	-
DQL29_RS06735 (NCTC12068_01335)	rimP	1336585..1337121 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQL29_RS06745 (NCTC12068_01337)	trmB	1337380..1338015 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL29_RS06750 (NCTC12068_01338)	ccrZ	1338015..1338806 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL29_RS06755 (NCTC12068_01339)	-	1338870..1339904 (-)	1035	WP_030126324.1	ABC transporter permease	-
DQL29_RS06760 (NCTC12068_01340)	pptA	1339907..1340632 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL29_RS06765 (NCTC12068_01341)	-	1340704..1341123 (+)	420	WP_002983376.1	HIT family protein	-
DQL29_RS06770 (NCTC12068_01342)	-	1341120..1341476 (+)	357	WP_030126323.1	hypothetical protein	-
DQL29_RS06775 (NCTC12068_01343)	brpA	1341587..1342870 (-)	1284	WP_030126322.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL29_RS06780 (NCTC12068_01344)	-	1342879..1343403 (-)	525	WP_030126321.1	GNAT family N-acetyltransferase	-
DQL29_RS06785 (NCTC12068_01345)	tsaE	1343378..1343839 (-)	462	WP_030126320.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL29_RS06790 (NCTC12068_01346)	-	1343993..1345453 (-)	1461	WP_030126319.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1138427 DQL29_RS06760 WP_002983379.1 1339907..1340632(-) (pptA) [Streptococcus pyogenes strain NCTC12068]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1138427 DQL29_RS06760 WP_002983379.1 1339907..1340632(-) (pptA) [Streptococcus pyogenes strain NCTC12068]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714