Detailed information NTG1138289

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQM51_RS07750
• Genome accession: NZ_LS483356
• Coordinates: 1460443..1461168 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC8230
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1455443..1466168

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM51_RS07715 (NCTC8230_01535)	rnpM	1455477..1455773 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQM51_RS07720 (NCTC8230_01536)	nusA	1455789..1456946 (-)	1158	WP_002983485.1	transcription termination factor NusA	-
DQM51_RS07725 (NCTC8230_01537)	rimP	1457121..1457657 (-)	537	WP_002983483.1	ribosome maturation factor RimP	-
DQM51_RS07735 (NCTC8230_01539)	trmB	1457916..1458551 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQM51_RS07740 (NCTC8230_01540)	ccrZ	1458551..1459342 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQM51_RS07745 (NCTC8230_01541)	-	1459406..1460440 (-)	1035	WP_002983381.1	ABC transporter permease	-
DQM51_RS07750 (NCTC8230_01542)	pptA	1460443..1461168 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQM51_RS07755 (NCTC8230_01543)	-	1461240..1461659 (+)	420	WP_002983376.1	HIT family protein	-
DQM51_RS07760 (NCTC8230_01544)	-	1461656..1462012 (+)	357	WP_002983373.1	hypothetical protein	-
DQM51_RS07765 (NCTC8230_01545)	brpA	1462123..1463406 (-)	1284	WP_002983372.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQM51_RS07770 (NCTC8230_01546)	-	1463415..1463939 (-)	525	WP_002983369.1	GNAT family N-acetyltransferase	-
DQM51_RS07775 (NCTC8230_01547)	tsaE	1463914..1464375 (-)	462	WP_002983367.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQM51_RS07780 (NCTC8230_01548)	-	1464529..1465989 (-)	1461	WP_002983366.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1138289 DQM51_RS07750 WP_002983379.1 1460443..1461168(-) (pptA) [Streptococcus pyogenes strain NCTC8230]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1138289 DQM51_RS07750 WP_002983379.1 1460443..1461168(-) (pptA) [Streptococcus pyogenes strain NCTC8230]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCTTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714