Detailed information NTG1138240

Bioinformatically predicted

Overview

• Name: treR
• Type: Regulator
• Locus tag: DQL02_RS08410
• Genome accession: NZ_LS483355
• Coordinates: 1666504..1667217 (+)
• Length: 237 a.a.
• NCBI ID: WP_002992823.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12067
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1668006..1669139	1666504..1667217	flank	789

Gene organization within MGE regions

Location: 1666504..1669139

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL02_RS08410 (NCTC12067_01667)	treR	1666504..1667217 (+)	714	WP_002992823.1	trehalose operon repressor	Regulator
DQL02_RS08420 (NCTC12067_01668)	-	1667496..1667827 (-)	332	Protein_1556	winged helix-turn-helix transcriptional regulator	-
DQL02_RS08425 (NCTC12067_01669)	-	1668006..1669139 (-)	1134	WP_014407456.1	ISAs1-like element IS1548 family transposase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27620.79 Da
• Isoelectric Point: 9.6307

>NTDB_id=1138240 DQL02_RS08410 WP_002992823.1 1666504..1667217(+) (treR) [Streptococcus pyogenes strain NCTC12067]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIRHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide

• Length: 714 bp

>NTDB_id=1138240 DQL02_RS08410 WP_002992823.1 1666504..1667217(+) (treR) [Streptococcus pyogenes strain NCTC12067]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAGACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACGCGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTCTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, gntR family (GntR) (3-66)

• UTRA domain (UTRA) (91-227)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
treR	Streptococcus mutans UA159	68.376	98.734	0.675