Detailed information NTG1138233

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL02_RS06560
• Genome accession: NZ_LS483355
• Coordinates: 1297045..1297770 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12067
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1292045..1302770

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL02_RS06525 (NCTC12067_01300)	rnpM	1292079..1292375 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQL02_RS06530 (NCTC12067_01301)	nusA	1292391..1293548 (-)	1158	WP_002983485.1	transcription termination factor NusA	-
DQL02_RS06535 (NCTC12067_01302)	rimP	1293723..1294259 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQL02_RS06545 (NCTC12067_01304)	trmB	1294518..1295153 (-)	636	WP_031488472.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL02_RS06550 (NCTC12067_01305)	ccrZ	1295153..1295944 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL02_RS06555 (NCTC12067_01306)	-	1296008..1297042 (-)	1035	WP_031577431.1	ABC transporter permease	-
DQL02_RS06560 (NCTC12067_01307)	pptA	1297045..1297770 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL02_RS06565 (NCTC12067_01308)	-	1297842..1298261 (+)	420	WP_002983376.1	HIT family protein	-
DQL02_RS06570 (NCTC12067_01309)	-	1298258..1298614 (+)	357	WP_031488470.1	hypothetical protein	-
DQL02_RS06575 (NCTC12067_01310)	brpA	1298725..1300008 (-)	1284	WP_031488469.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL02_RS06580 (NCTC12067_01311)	-	1300017..1300541 (-)	525	WP_031488468.1	GNAT family N-acetyltransferase	-
DQL02_RS06585 (NCTC12067_01312)	tsaE	1300516..1300977 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL02_RS06590 (NCTC12067_01313)	-	1301131..1302591 (-)	1461	WP_031488467.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1138233 DQL02_RS06560 WP_002983379.1 1297045..1297770(-) (pptA) [Streptococcus pyogenes strain NCTC12067]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1138233 DQL02_RS06560 WP_002983379.1 1297045..1297770(-) (pptA) [Streptococcus pyogenes strain NCTC12067]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714