Detailed information NTG1138063

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL37_RS07475
• Genome accession: NZ_LS483352
• Coordinates: 1420558..1421283 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12052
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1415558..1426283

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL37_RS07440 (NCTC12052_01478)	rnpM	1415592..1415888 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQL37_RS07445 (NCTC12052_01479)	nusA	1415904..1417061 (-)	1158	WP_002994325.1	transcription termination factor NusA	-
DQL37_RS07450 (NCTC12052_01480)	rimP	1417236..1417772 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQL37_RS07460 (NCTC12052_01482)	trmB	1418031..1418666 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL37_RS07465 (NCTC12052_01483)	ccrZ	1418666..1419457 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL37_RS07470 (NCTC12052_01484)	-	1419521..1420555 (-)	1035	WP_010922583.1	ABC transporter permease	-
DQL37_RS07475 (NCTC12052_01485)	pptA	1420558..1421283 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL37_RS07480 (NCTC12052_01486)	-	1421355..1421774 (+)	420	WP_002983376.1	HIT family protein	-
DQL37_RS07485 (NCTC12052_01487)	-	1421771..1422127 (+)	357	WP_002988657.1	hypothetical protein	-
DQL37_RS07490 (NCTC12052_01488)	brpA	1422238..1423512 (-)	1275	WP_020837594.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL37_RS07495 (NCTC12052_01489)	-	1423521..1424045 (-)	525	WP_009880752.1	GNAT family N-acetyltransferase	-
DQL37_RS07500 (NCTC12052_01490)	tsaE	1424020..1424481 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL37_RS07505 (NCTC12052_01491)	-	1424635..1426095 (-)	1461	WP_002988645.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1138063 DQL37_RS07475 WP_002983379.1 1420558..1421283(-) (pptA) [Streptococcus pyogenes strain NCTC12052]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1138063 DQL37_RS07475 WP_002983379.1 1420558..1421283(-) (pptA) [Streptococcus pyogenes strain NCTC12052]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714