Detailed information NTG1137914

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: DQM59_RS09600
• Genome accession: NZ_LS483349
• Coordinates: 1868016..1870457 (-)
• Length: 813 a.a.
• NCBI ID: WP_002279992.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain NCTC10449
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1863016..1875457

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM59_RS09585 (NCTC10449_01863)	rpsJ	1863837..1864145 (-)	309	WP_002262341.1	30S ribosomal protein S10	-
DQM59_RS09590 (NCTC10449_01864)	-	1864465..1865151 (+)	687	WP_002266894.1	helix-turn-helix domain-containing protein	-
DQM59_RS09595 (NCTC10449_01865)	-	1865342..1867729 (-)	2388	WP_002279993.1	glycoside hydrolase family 68 protein	-
DQM59_RS09600 (NCTC10449_01866)	clpC	1868016..1870457 (-)	2442	WP_002279992.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DQM59_RS09605 (NCTC10449_01867)	ctsR	1870454..1870918 (-)	465	WP_002262345.1	transcriptional regulator CtsR	-
DQM59_RS09610 (NCTC10449_01868)	tsf	1871199..1872245 (-)	1047	WP_002266891.1	translation elongation factor Ts	-
DQM59_RS09615 (NCTC10449_01869)	rpsB	1872312..1873097 (-)	786	WP_002262347.1	30S ribosomal protein S2	-
DQM59_RS09620 (NCTC10449_01870)	-	1873287..1875140 (-)	1854	WP_002279991.1	hypothetical protein	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90316.10 Da
• Isoelectric Point: 6.9065

>NTDB_id=1137914 DQM59_RS09600 WP_002279992.1 1868016..1870457(-) (clpC) [Streptococcus mutans strain NCTC10449]
MTDYSLKMQEVFRLAQFEAARFESSYLESWHVLLAMVEIDSSVAGLSFAEFEADVRFEDYQAAAILAIGKKPKSSSNDIM
LLEQSHALKRTLAEAAAISQVTHAKEVGTEHVLFAMLLNPNLLATRILELVGFHAKDDGESIRLLDLRKVIERYAGFSKE
DIKAIFEMRKPKKVKNSSSFSDLMKPPSVTGELADFTRDLTELARQGRLEPVIGREQEISRMVQILSRKTKNNPVLVGDA
GVGKTALAYGLAQRIVDSAVPFELADMKVLELDMMSVVAGTRFRGDFEERMNQIIADIEADGHIVLFIDELHTIMGSGSG
IDSTLDAANILKPALARGSLRTIGATTQEEYQKHIEKDAALSRRFAKVTIEEPSEEEAYQILLGLKKSYETYHHVIISDA
AVMAAVKGAHRYLSGKNLPDSAIDLLDEASATVQGLVKKKAPAYLTDLDHALITNDYQLAKRLLKKEKKPLLKKRAEVKE
EDILATLSKLSGIPVKKLTQADSKKYLNLERELHKRVIGQDDAVSSISRAIRRNQSGIRVGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNILLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKSFSQDYKAMESRILEELKKVYRPEFINRIDEKVVFHN
LGQEDIRHVVKIMVAPLIAHLADQGITLKFQPSALKHLALAGYDAEMGARPLRRTLQTEVEDKLAELILSGKLASGQTLK
IGIQKEKLKFDIV

Nucleotide

• Length: 2442 bp

>NTDB_id=1137914 DQM59_RS09600 WP_002279992.1 1868016..1870457(-) (clpC) [Streptococcus mutans strain NCTC10449]
ATGACCGATTACTCATTAAAAATGCAGGAAGTCTTTCGATTGGCGCAGTTTGAAGCAGCTCGTTTTGAAAGTTCCTATTT
AGAAAGCTGGCATGTCCTTCTTGCAATGGTAGAGATTGATTCCTCAGTGGCTGGTTTAAGTTTTGCGGAGTTTGAAGCAG
ATGTCCGTTTTGAGGATTATCAGGCTGCTGCTATTTTGGCGATTGGTAAAAAGCCTAAGTCCTCGAGTAATGATATTATG
CTTTTAGAGCAATCACATGCTTTAAAACGAACCCTAGCAGAGGCCGCTGCTATTAGTCAGGTGACACACGCTAAAGAAGT
CGGCACAGAACATGTTCTCTTTGCTATGTTACTGAATCCTAATCTTTTGGCGACTCGCATTTTAGAATTAGTTGGTTTTC
ACGCCAAAGATGATGGAGAGTCCATCCGTCTTTTGGATCTGCGAAAAGTGATTGAACGTTATGCTGGCTTTTCCAAAGAG
GACATTAAGGCCATCTTTGAAATGCGTAAACCTAAAAAGGTCAAAAATAGCAGCAGCTTTTCTGATTTAATGAAGCCACC
TAGCGTTACAGGTGAACTAGCTGATTTTACACGGGATTTGACGGAGTTGGCAAGACAAGGTCGTTTAGAACCTGTTATTG
GCCGTGAACAAGAAATTTCACGGATGGTTCAAATTTTAAGCCGTAAGACAAAAAATAACCCTGTTTTAGTTGGCGATGCT
GGTGTTGGGAAGACGGCCTTGGCTTACGGCCTTGCTCAACGTATTGTGGATAGTGCCGTTCCTTTTGAATTGGCAGATAT
GAAAGTACTAGAGCTCGATATGATGAGTGTTGTTGCAGGGACTCGTTTTCGTGGCGATTTTGAGGAACGAATGAATCAAA
TTATTGCAGACATTGAAGCAGATGGTCACATTGTCCTCTTCATTGATGAGCTGCATACCATTATGGGTTCAGGAAGTGGT
ATTGATAGTACGCTGGATGCTGCTAATATTCTTAAACCAGCTTTAGCGCGCGGCAGTCTTAGAACGATTGGAGCGACTAC
TCAAGAGGAGTATCAAAAGCATATTGAAAAAGATGCTGCTCTTTCTCGCCGTTTTGCTAAGGTAACTATTGAAGAACCAA
GTGAAGAAGAAGCTTATCAGATCTTGCTTGGTTTAAAGAAGAGTTATGAAACTTATCATCATGTTATTATTTCTGATGCA
GCCGTAATGGCGGCAGTCAAAGGAGCACATCGTTATTTAAGTGGTAAAAATTTACCTGATTCGGCTATCGATCTTTTAGA
TGAAGCTAGTGCAACTGTTCAAGGCTTAGTGAAAAAAAAGGCACCAGCTTATTTGACAGATTTAGATCATGCTCTTATCA
CTAACGATTACCAATTAGCTAAGCGTTTGCTGAAAAAGGAGAAGAAGCCTCTACTTAAAAAACGAGCTGAAGTCAAGGAA
GAAGATATCCTAGCTACTCTCAGCAAACTTTCAGGCATCCCTGTCAAAAAATTAACACAGGCTGACAGTAAAAAGTACCT
TAATCTCGAAAGGGAATTACATAAGCGTGTAATTGGTCAAGACGATGCGGTGTCCAGTATCAGCCGTGCTATTCGCCGCA
ATCAATCCGGAATTCGGGTTGGCAAACGTCCCATTGGCTCTTTCATGTTTTTGGGGCCGACAGGTGTTGGTAAAACAGAG
CTTGCTAAGGCTTTGGCAGAAGTGCTTTTTGATGATGAGTCAGCTCTTATTCGTTTTGACATGAGCGAATATATGGAAAA
ATTTGCAGCTTCTCGCCTTAATGGAGCTCCTCCGGGCTATGTGGGGTATGAAGAAGGCGGTGAGTTGACGGAAAAGGTTC
GTAACAAACCTTACTCTGTTCTTCTTTTTGATGAGGTGGAAAAAGCTCATCCAGATATTTTCAATATCTTACTTCAAGTA
CTTGATGATGGTGTTTTGACAGATAGCCGTGGTCGCAAAGTTGATTTTTCAAATACGATTATTATCATGACCTCTAATTT
GGGTGCGACTGCGCTTCGTGATGATAAAACCGTTGGTTTTGGAGCTAAAAGCTTTTCCCAGGATTATAAGGCCATGGAAA
GTCGTATTTTAGAGGAATTAAAAAAGGTTTACCGACCTGAATTTATTAATCGTATTGATGAAAAAGTTGTCTTTCATAAC
CTTGGTCAAGAAGACATACGCCATGTTGTTAAAATTATGGTTGCTCCATTGATTGCCCATTTGGCTGATCAGGGGATTAC
ACTTAAGTTTCAGCCTTCAGCTTTGAAACATTTAGCTCTGGCAGGTTATGATGCTGAAATGGGGGCACGTCCTTTGCGTC
GGACACTTCAGACAGAAGTGGAAGATAAGTTAGCAGAGCTTATTCTTTCGGGAAAACTAGCTAGTGGACAGACTCTGAAA
ATAGGTATTCAAAAAGAAAAATTAAAATTTGATATTGTATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (105-133)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-55)

• AAA lid domain (AAA_lid_9) (374-461)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-366)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	99.877	100	0.999
clpC	Streptococcus thermophilus LMD-9	72.426	100	0.727
clpC	Streptococcus thermophilus LMG 18311	72.304	100	0.726
clpC	Streptococcus pneumoniae TIGR4	67.076	100	0.672
clpC	Streptococcus pneumoniae Rx1	67.076	100	0.672
clpC	Streptococcus pneumoniae D39	67.076	100	0.672
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.98	100	0.502
clpC	Bacillus subtilis subsp. subtilis str. 168	43.705	100	0.444
clpE	Streptococcus pneumoniae TIGR4	47.2	76.876	0.363
clpE	Streptococcus pneumoniae Rx1	47.2	76.876	0.363
clpE	Streptococcus pneumoniae D39	47.2	76.876	0.363
clpE	Streptococcus pneumoniae R6	47.2	76.876	0.363
clpE	Streptococcus mutans UA159	47.04	76.876	0.362