Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   DQM59_RS03940 Genome accession   NZ_LS483349
Coordinates   742186..743079 (-) Length   297 a.a.
NCBI ID   WP_002272311.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCTC10449     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 737186..748079
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM59_RS03910 (NCTC10449_00757) cas1 739174..740040 (+) 867 WP_002280231.1 type II CRISPR-associated endonuclease Cas1 -
  DQM59_RS03915 (NCTC10449_00758) cas2 740037..740381 (+) 345 WP_002263547.1 CRISPR-associated endonuclease Cas2 -
  DQM59_RS03920 (NCTC10449_00759) csn2 740371..741033 (+) 663 WP_002263546.1 type II-A CRISPR-associated protein Csn2 -
  DQM59_RS03925 (NCTC10449_00760) - 741130..741321 (+) 192 WP_002265423.1 type II toxin-antitoxin system HicA family toxin -
  DQM59_RS03930 (NCTC10449_00761) - 741339..741716 (+) 378 WP_002269450.1 type II toxin-antitoxin system HicB family antitoxin -
  DQM59_RS03935 - 741814..742080 (-) 267 WP_050560078.1 hypothetical protein -
  DQM59_RS03940 (NCTC10449_00764) irvR 742186..743079 (-) 894 WP_002272311.1 LexA family transcriptional regulator IrvR Regulator
  DQM59_RS03945 (NCTC10449_00765) - 743395..743679 (+) 285 WP_002262720.1 helix-turn-helix transcriptional regulator -
  DQM59_RS03950 (NCTC10449_00766) gbpC 743842..745593 (+) 1752 WP_002279994.1 glucan-binding protein GbpC -
  DQM59_RS10465 - 745723..745953 (+) 231 WP_018110186.1 hypothetical protein -
  DQM59_RS10555 (NCTC10449_00767) - 745988..746116 (+) 129 WP_002262718.1 hypothetical protein -

Sequence

Protein


Download         Length: 297 a.a.        Molecular weight: 33625.32 Da        Isoelectric Point: 6.7036

>NTDB_id=1137883 DQM59_RS03940 WP_002272311.1 742186..743079(-) (irvR) [Streptococcus mutans strain NCTC10449]
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFA
SKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQDETASLSASDETTDDKVADKSNHTQYQKVVDSFIAKELNDQTI
IHWDNVIKAKDLYQTFGRQYENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALTVNGNSMEPLFYNGDVIFVKKT
KAIHHGQIIVVIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT

Nucleotide


Download         Length: 894 bp        

>NTDB_id=1137883 DQM59_RS03940 WP_002272311.1 742186..743079(-) (irvR) [Streptococcus mutans strain NCTC10449]
ATGGGACGCGGTAAATTAACTCCACAAGATTTAGAAGCAATGAAGGCTATTTCTGCCAATCTTCAAAGACTTCTAGCTGA
GAGCGGAATGAAACAATCTCACTTAGCCACTATCCTTAACATTCCTACAAGTAGTCTTAATGAATATGTTAAAGGAAAGA
GTTTGCCAAAAATAGGGAATATTCAAAAAATCGCAGATTACTTTGGTCTCCAAAAATCCGATATTGACCCTAGATTTGCA
AGTAAAAAGGACTCTTCTACTCTTGATAAAATTAATCATATTGCCAAACAATTAGAAATGAAGAGACAGATAAAAGTCTT
AGATTTCTGTTACCAACAATCAAAGGAACAAGATGAAACAGCAAGCTTATCTGCCAGTGATGAAACGACTGATGATAAAG
TTGCTGACAAATCAAATCATACGCAGTATCAAAAGGTTGTTGATTCTTTTATTGCCAAAGAATTAAACGATCAGACAATT
ATTCATTGGGATAATGTGATAAAAGCTAAGGATTTGTATCAAACCTTTGGACGTCAATACGAAAACATTCAGATTTATGG
TGAAGTTTCAGCTGGTACTGGTATCTGGGTTGGACATGAAAAACAAGAAACCATTAAATACCCAATACCAATTCCAGAAC
ATGATATTGCTCTTACTGTCAATGGTAATAGTATGGAACCTTTATTTTACAACGGTGACGTTATTTTTGTTAAAAAGACT
AAAGCTATCCATCACGGACAAATTATCGTTGTTATTGTAAATAATGAGGCATATGTCAAAAAACTCTACCGAAAAAACAA
AGAAATTCGACTCATCTCATTAAATCCAGATTATGATGACATCATTTTAAAAGAAGATGATACAATTGAAGTCATCGGAA
CGGTCATTACCTAA

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(22-70)

Peptidase S24-like (Peptidase_S24)

(184-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

99.327

100

0.993

Multiple sequence alignment