Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   DQM73_RS01035 Genome accession   NZ_LS483346
Coordinates   184638..187067 (+) Length   809 a.a.
NCBI ID   WP_002926285.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC11085     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 179638..192067
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM73_RS01010 (NCTC11085_00196) - 179733..181073 (+) 1341 WP_002926296.1 ISLre2 family transposase -
  DQM73_RS01015 (NCTC11085_00197) rpsB 181535..182317 (+) 783 WP_002894015.1 30S ribosomal protein S2 -
  DQM73_RS01020 (NCTC11085_00198) tsf 182390..183433 (+) 1044 WP_002926293.1 translation elongation factor Ts -
  DQM73_RS01025 (NCTC11085_00199) - 183538..184026 (-) 489 WP_162091651.1 hypothetical protein -
  DQM73_RS01030 (NCTC11085_00200) - 184173..184637 (+) 465 WP_002926288.1 CtsR family transcriptional regulator -
  DQM73_RS01035 (NCTC11085_00201) clpC 184638..187067 (+) 2430 WP_002926285.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DQM73_RS01040 (NCTC11085_00202) - 187161..187904 (+) 744 WP_002926284.1 DUF4272 domain-containing protein -
  DQM73_RS01045 (NCTC11085_00203) - 187947..188432 (+) 486 WP_002926282.1 hypothetical protein -
  DQM73_RS01050 (NCTC11085_00204) - 188416..188817 (+) 402 WP_002926281.1 DUF4430 domain-containing protein -
  DQM73_RS01055 (NCTC11085_00205) - 189004..190062 (+) 1059 WP_002926279.1 AAA family ATPase -
  DQM73_RS01060 (NCTC11085_00206) pnuC 190084..190899 (+) 816 WP_002926275.1 nicotinamide riboside transporter PnuC -
  DQM73_RS01065 (NCTC11085_00207) - 190954..191742 (+) 789 WP_002926274.1 NUDIX hydrolase -

Sequence

Protein


Download         Length: 809 a.a.        Molecular weight: 89734.35 Da        Isoelectric Point: 5.2508

>NTDB_id=1137676 DQM73_RS01035 WP_002926285.1 184638..187067(+) (clpC) [Streptococcus sanguinis strain NCTC11085]
MKYSKALIESLEAAQLLAGHFTTDYLESWHLLIALANNPYSVAGSVLNEFPVEVDGFEEAAFQITGQAYQKDGHFELLPF
SYRLEELFEEAGQIAEAVRAKHVGTEHVLLAMLFDRGTLASRILEFTGFSYEDKEQGPKISDLRKVLEQRAGWGKEDIKA
IRSLNKGVMAAKQTMANMMGMPASTSGGLEDYTRDLTELARDGRLEPVIGRDQEISRIVQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVAAGQVPAELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEEDGHVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVSIEEPNVADSIAILQGLRKSYEDHHKVQISDQAIET
AVKYAHRYLTSKHLPDSAIDLLDEASATVQNRGTQNYEQSDLTPVDQALMAADFKKVSRLLEQEQQPKLYKLKVEEDDVL
ATLSGLSGIPVQKLTQTDAKKYLNLETELHKRVIGQDEAISAISRAIRRNQSGIRSSKRPIGSFMFLGPTGVGKTELAKA
LAESLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
QLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFVARDIRLDHANMEKRMLEELKKAYRPEFINRIDEKVVFHSLSAE
DMQEVVKVMVKPLIVSLADKGIELKFQASALKLLAQEGYDVEMGARPLRRTLQTQVEDKLSELLLTGDLTTGQTLKVGVK
AGQLKFEMA

Nucleotide


Download         Length: 2430 bp        

>NTDB_id=1137676 DQM73_RS01035 WP_002926285.1 184638..187067(+) (clpC) [Streptococcus sanguinis strain NCTC11085]
ATGAAATACTCAAAAGCCTTAATAGAAAGCTTGGAAGCAGCCCAGCTCTTGGCCGGCCATTTTACGACAGATTATCTGGA
ATCATGGCATCTGCTGATTGCTCTGGCTAATAATCCCTACAGCGTTGCTGGCTCAGTCCTCAATGAGTTTCCTGTGGAAG
TTGATGGATTTGAAGAAGCGGCTTTTCAGATTACTGGTCAGGCTTATCAGAAAGACGGTCACTTCGAGCTGCTGCCTTTT
TCTTATCGCTTAGAGGAGCTGTTTGAGGAAGCGGGGCAGATTGCAGAAGCTGTTCGGGCTAAGCATGTAGGTACTGAGCA
TGTGCTGCTGGCCATGCTATTTGACCGGGGGACCTTGGCCTCTCGTATTCTGGAATTTACCGGCTTTAGCTACGAGGACA
AAGAGCAGGGGCCGAAAATCAGTGATTTGCGAAAGGTCTTGGAGCAGCGAGCTGGCTGGGGCAAGGAAGATATCAAGGCT
ATTCGCAGTCTGAATAAGGGAGTAATGGCCGCTAAGCAGACCATGGCCAATATGATGGGTATGCCAGCTTCTACCAGCGG
GGGGCTAGAAGACTACACTCGAGATTTGACGGAGCTGGCTAGAGATGGCCGATTGGAGCCCGTAATTGGCCGTGATCAGG
AAATTTCACGAATAGTTCAGATTCTCAGTCGCAAGACTAAAAACAATCCAGTGCTGGTTGGAGATGCTGGGGTTGGTAAG
ACAGCTCTGGCTTTAGGTCTGGCCCAGCGTGTGGCAGCTGGTCAGGTTCCTGCTGAACTTGCCAAGATGCGGGTTTTGGA
ACTGGACTTGATGAATGTAGTTGCTGGAACTCGCTTTCGCGGAGATTTCGAGGAGCGGATGAACAACATCATCAATGACA
TTGAAGAAGATGGTCATGTTATTCTTTTCATCGATGAACTTCATACCATCATGGGCTCTGGCAGCGGTATTGACTCAACC
TTGGATGCGGCCAATATCCTGAAACCGGCTCTGGCTCGCGGAACTCTGCGGACAGTTGGCGCTACGACGCAGGAAGAGTA
CCAGAAACATATTGAAAAAGATGCGGCCCTTTCCCGGCGTTTTGCCAAGGTCAGCATAGAAGAGCCTAATGTGGCTGACA
GCATTGCTATTTTACAAGGCTTGAGAAAGAGCTATGAGGACCATCACAAGGTGCAGATTAGTGATCAAGCGATTGAGACG
GCGGTGAAATATGCCCATCGCTATCTGACTAGCAAGCATCTGCCGGACTCTGCCATTGATCTTTTGGACGAGGCCAGTGC
GACAGTGCAGAATAGAGGGACACAGAATTACGAGCAGTCGGATTTGACGCCAGTGGATCAAGCCTTGATGGCAGCGGACT
TTAAAAAGGTGTCGAGGCTGCTTGAGCAAGAGCAGCAACCCAAGCTCTATAAACTGAAAGTGGAAGAAGACGATGTCTTG
GCTACTCTTAGTGGCTTGTCTGGGATTCCTGTGCAGAAGCTGACTCAGACAGATGCGAAGAAATACCTCAATTTGGAAAC
AGAACTGCATAAACGCGTGATTGGGCAGGACGAGGCGATTTCAGCTATCAGCCGAGCTATCCGACGGAACCAGTCTGGTA
TCCGCAGCAGCAAGCGGCCGATCGGATCTTTTATGTTCCTAGGTCCGACAGGAGTCGGGAAGACAGAGCTAGCCAAGGCT
TTGGCCGAAAGTCTCTTTGATGACGAGTCTGCTCTCATACGATTTGATATGAGTGAGTACATGGAGAAATTCGCGGCTAG
TCGCCTCAACGGAGCGCCTCCAGGCTATGTAGGCTATGAAGAAGGAGGGGAGCTGACGGAAAAGGTGCGCAACCGACCTT
ATTCTGTCCTGCTCTTTGACGAAGTGGAAAAGGCGCATCCAGATATTTTCAATGTCCTCCTGCAGGTCTTGGATGATGGT
CAACTGACTGACAGCAAGGGCCGCAAGGTGGACTTCTCCAACACGATTATTATCATGACCAGCAATCTGGGGGCAACTAG
TTTGCGGGATGATAAGACGGTGGGCTTTGTAGCGCGGGATATTCGCTTGGACCATGCCAATATGGAAAAACGGATGCTGG
AAGAGCTTAAGAAAGCTTATCGACCAGAGTTTATCAACCGTATCGACGAAAAGGTAGTTTTCCACAGCTTATCTGCAGAA
GATATGCAGGAAGTGGTCAAGGTTATGGTCAAACCGCTCATTGTCAGTCTTGCTGATAAGGGAATTGAGCTGAAGTTCCA
GGCTAGTGCCCTTAAGCTGCTGGCTCAGGAAGGCTACGATGTGGAAATGGGGGCACGGCCATTGCGCCGCACTCTGCAGA
CCCAGGTAGAGGACAAGTTGTCTGAGCTACTTTTGACAGGAGATTTGACAACGGGTCAAACTCTTAAGGTCGGAGTCAAA
GCTGGCCAACTCAAGTTTGAAATGGCCTAG

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(371-459)

ATPase family associated with various cellular activities (AAA) (AAA)

(231-362)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(717-797)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(14-60)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(100-133)

AAA domain (Cdc48 subfamily) (AAA_2)

(539-710)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus pneumoniae Rx1

77.284

100

0.774
  clpC Streptococcus pneumoniae D39

77.284

100

0.774
  clpC Streptococcus pneumoniae TIGR4

77.284

100

0.774
  clpC Streptococcus mutans UA159

68.148

100

0.682
  clpC Streptococcus thermophilus LMG 18311

66.831

100

0.67
  clpC Streptococcus thermophilus LMD-9

66.708

100

0.669
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

50.605

100

0.517
  clpC Bacillus subtilis subsp. subtilis str. 168

45.387

99.135

0.45
  clpE Streptococcus mutans UA159

47.343

76.761

0.363

Multiple sequence alignment