Detailed information NTG1137422

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: DQL04_RS03215
• Genome accession: NZ_LS483340
• Coordinates: 617266..619548 (-)
• Length: 760 a.a.
• NCBI ID: WP_047235755.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12062
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 612266..624548

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL04_RS03200 (NCTC12062_00628)	ileS	613264..616065 (+)	2802	WP_047235754.1	isoleucine--tRNA ligase	-
DQL04_RS03205 (NCTC12062_00629)	-	616330..616632 (-)	303	WP_002983878.1	DUF1827 family protein	-
DQL04_RS03210 (NCTC12062_00630)	-	616683..617138 (-)	456	WP_002989103.1	NUDIX hydrolase	-
DQL04_RS03215 (NCTC12062_00631)	clpE	617266..619548 (-)	2283	WP_047235755.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DQL04_RS03220 (NCTC12062_00632)	-	619846..620076 (+)	231	WP_002983885.1	YkuJ family protein	-
DQL04_RS03225 (NCTC12062_00633)	-	620203..620889 (+)	687	WP_047235756.1	amino acid ABC transporter permease	-
DQL04_RS03230 (NCTC12062_00634)	-	620889..621623 (+)	735	WP_002989107.1	amino acid ABC transporter ATP-binding protein	-
DQL04_RS03235 (NCTC12062_00635)	-	621772..623181 (+)	1410	WP_002993337.1	cryptochrome/photolyase family protein	-

Sequence

Protein

• Length: 760 a.a.
• Molecular weight: 84708.84 Da
• Isoelectric Point: 5.0123

>NTDB_id=1137422 DQL04_RS03215 WP_047235755.1 617266..619548(-) (clpE) [Streptococcus pyogenes strain NCTC12062]
MLCQNCNLNESTIHLYTSVNGKQRQVDLCQNCYQIMKSDPANSILNGLTPGYRAQDRSTSPFFDDFFGDLNNFRAFGNLP
NTPPTQAGQNGNGGGRYGGNYNGQRPAQPQTSNQQAKGLLEEFGINVTDIARNGNIDPVIGRDEEITRVIEILNRRTKNN
PVLIGEPGVGKTAVVEGLAQKIIDGTVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHH
VKYSPAAIEAAAHLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDKRLIEAENLKAQATRDEDYERAAYFRDQ
ITKYKEMQAQKVDEQDIPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVNLANDLKAHVIGQDDAVDKIAKAIRRNRVGL
GTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSTNNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPY
SLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTSSVLGELSNFFS
PEFMNRFDGIIEFKALSKEHLLHIVDLMLEDVNERLGYNGIHLDVTQKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAIT
DYYLEHPTEKQLRALMTNSENITIKAVKEGDSFLNEESLD

Nucleotide

• Length: 2283 bp

>NTDB_id=1137422 DQL04_RS03215 WP_047235755.1 617266..619548(-) (clpE) [Streptococcus pyogenes strain NCTC12062]
ATGCTGTGTCAAAATTGTAATTTAAACGAATCTACTATTCATCTTTATACAAGTGTTAATGGAAAACAAAGACAGGTTGA
TCTCTGTCAAAATTGTTATCAAATCATGAAATCCGATCCTGCCAATTCTATTTTAAATGGCCTAACCCCAGGATATAGAG
CACAAGATAGATCCACAAGTCCTTTCTTTGATGACTTTTTTGGTGATTTGAATAATTTTAGAGCTTTTGGTAATCTTCCA
AATACCCCACCTACTCAGGCAGGGCAAAATGGAAATGGCGGAGGACGCTATGGTGGTAACTACAACGGACAACGACCTGC
TCAGCCACAAACATCAAATCAGCAAGCAAAGGGCTTGTTAGAAGAGTTTGGGATTAATGTCACAGATATTGCAAGAAATG
GTAATATTGATCCTGTTATTGGTCGTGACGAAGAGATTACACGCGTTATCGAGATCCTCAACCGCCGTACTAAAAATAAT
CCTGTGCTAATTGGTGAGCCTGGAGTTGGTAAAACTGCTGTTGTAGAAGGTTTGGCTCAAAAAATTATTGATGGTACTGT
TCCTCAAAAACTCCAAGGCAAGCAAGTGATTCGTCTTGATGTGGTTAGCCTCGTTCAGGGAACAGGTATCCGTGGTCAGT
TTGAAGAGCGCATGCAAAAATTAATGGAAGAAATTCGCAATCGCAAGGATGTGATTCTCTTTATTGATGAAATTCATGAG
ATTGTCGGTGCTGGTTCTGCAGGAGACGGCAATATGGATGCTGGTAATATTTTAAAACCAGCCTTGGCCCGTGGTGAGTT
GCAACTCGTTGGTGCTACTACATTAAATGAATACCGTATTATTGAAAAAGACGCTGCCTTAGAACGACGTATGCAACCCG
TTAAAGTTGATGAACCTTCTGTTGAGGAAACCATCACGATTTTAAAAGGTATCCAACCGAAATACGAAGACTATCATCAT
GTCAAATATAGCCCAGCCGCTATTGAAGCTGCCGCTCATTTATCTAACCGCTATATTCAAGACCGTTTTCTTCCTGATAA
GGCTATTGATCTTCTGGACGAAGCTGGTTCCAAAATGAATCTAACCCTCAACTTTGTTGATCCTAAAGAAATTGACAAAC
GTCTTATTGAAGCTGAGAATCTCAAGGCGCAAGCTACTCGAGACGAAGACTATGAACGCGCAGCTTATTTCCGCGATCAA
ATTACAAAATACAAAGAAATGCAGGCTCAAAAAGTCGATGAGCAAGATATTCCCATCATTACTGAAAAAACCATTGAAGC
TATTGTAGAGCAAAAAACTAATATTCCAGTTGGGGACTTAAAAGAAAAGGAACAGTCTCAACTCGTAAACTTAGCCAATG
ATCTGAAAGCACACGTGATCGGGCAAGACGATGCTGTTGATAAAATCGCTAAGGCTATTCGTCGTAACCGTGTGGGATTA
GGAACTCCAAATCGCCCTATTGGTTCTTTCTTATTCGTTGGACCGACTGGGGTTGGTAAAACTGAATTGTCTAAACAACT
AGCCATTGAACTCTTTGGTTCGACAAACAATATGATTCGCTTTGACATGTCCGAATACATGGAAAAACACGCTGTCGCCA
AATTAGTCGGGGCTCCTCCAGGTTATGTCGGCTATGAAGAAGCTGGACAGCTAACCGAACAAGTTCGTCGCAATCCATAT
TCACTTATTCTCTTAGATGAGGTGGAAAAAGCCCATCCTGACGTCATGCACATGTTCTTACAAGTTCTTGATGACGGTCG
CTTAACAGACGGCCAAGGACGAACAGTCAGCTTCAAGGACACCATTATTATCATGACCTCTAATGCCGGAACAGGTAAAA
GCGAAGCTTCTGTCGGATTTGGTGCTGCTAGAGAAGGACGGACAAGTTCTGTCCTTGGTGAATTAAGCAACTTCTTCAGC
CCAGAGTTTATGAATCGTTTCGATGGTATTATTGAATTCAAAGCTTTATCTAAAGAGCATTTGCTGCATATCGTTGATTT
AATGCTGGAAGATGTTAATGAGCGCTTAGGCTATAATGGGATTCATCTTGATGTGACACAAAAGGTCAAAGAAAAATTAG
TAGATTTAGGCTATGATCCTAAAATGGGCGCTCGGCCGCTCCGTCGTACTATCCAAGATTATATAGAAGATGCCATTACA
GACTATTATTTAGAGCACCCAACTGAAAAACAGTTACGTGCACTGATGACAAACAGTGAAAATATCACGATTAAAGCTGT
TAAAGAGGGAGATTCTTTTCTTAACGAAGAGTCTCTCGATTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (300-397)

• ATPase family associated with various cellular activities (AAA) (AAA) (162-281)

• AAA domain (Cdc48 subfamily) (AAA_2) (485-648)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (656-729)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.492	98.421	0.832
clpE	Streptococcus pneumoniae Rx1	82.423	98.816	0.814
clpE	Streptococcus pneumoniae D39	82.423	98.816	0.814
clpE	Streptococcus pneumoniae R6	82.423	98.816	0.814
clpE	Streptococcus pneumoniae TIGR4	82.29	98.816	0.813
clpC	Lactococcus lactis subsp. cremoris KW2	75.132	100	0.751
clpC	Bacillus subtilis subsp. subtilis str. 168	51.593	86.711	0.447
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46	85.526	0.393
clpC	Streptococcus pneumoniae Rx1	47.68	82.237	0.392
clpC	Streptococcus pneumoniae D39	47.68	82.237	0.392
clpC	Streptococcus pneumoniae TIGR4	47.68	82.237	0.392
clpC	Streptococcus mutans UA159	47.573	81.316	0.387
clpC	Streptococcus thermophilus LMD-9	47.106	81.842	0.386
clpC	Streptococcus thermophilus LMG 18311	46.785	81.842	0.383