Detailed information NTG1137421

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQL04_RS03095
• Genome accession: NZ_LS483340
• Coordinates: 592808..593845 (+)
• Length: 345 a.a.
• NCBI ID: WP_047235746.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12062
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 587808..598845

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL04_RS03070 (NCTC12062_00602)	-	588072..589403 (+)	1332	WP_011054719.1	dipeptidase	-
DQL04_RS03075 (NCTC12062_00603)	arcC	589423..590373 (+)	951	WP_011528820.1	carbamate kinase	-
DQL04_RS03080 (NCTC12062_00604)	asnA	590686..591678 (+)	993	WP_002983817.1	aspartate--ammonia ligase	-
DQL04_RS03085 (NCTC12062_00605)	rsmD	591801..592340 (+)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQL04_RS03090 (NCTC12062_00606)	coaD	592330..592821 (+)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
DQL04_RS03095 (NCTC12062_00607)	sepM	592808..593845 (+)	1038	WP_047235746.1	SepM family pheromone-processing serine protease	Regulator
DQL04_RS03100 (NCTC12062_00608)	-	594259..595236 (+)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
DQL04_RS03105 (NCTC12062_00609)	-	595684..596304 (+)	621	WP_168681594.1	YutD family protein	-
DQL04_RS03110 (NCTC12062_00610)	rlmN	596308..597387 (+)	1080	WP_111698572.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DQL04_RS03115 (NCTC12062_00611)	-	597469..598095 (-)	627	WP_002983834.1	prepilin peptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37555.27 Da
• Isoelectric Point: 9.6692

>NTDB_id=1137421 DQL04_RS03095 WP_047235746.1 592808..593845(+) (sepM) [Streptococcus pyogenes strain NCTC12062]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPITTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=1137421 DQL04_RS03095 WP_047235746.1 592808..593845(+) (sepM) [Streptococcus pyogenes strain NCTC12062]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGGGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTATTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.986	100	0.69