Detailed information NTG1137416

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL04_RS02260
• Genome accession: NZ_LS483340
• Coordinates: 425549..426274 (+)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12062
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 420549..431274

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL04_RS02230 (NCTC12062_00440)	-	420728..422188 (+)	1461	WP_012560892.1	NCS2 family permease	-
DQL04_RS02235 (NCTC12062_00441)	tsaE	422342..422803 (+)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL04_RS02240 (NCTC12062_00442)	-	422778..423302 (+)	525	WP_020905405.1	GNAT family N-acetyltransferase	-
DQL04_RS02245 (NCTC12062_00443)	brpA	423311..424594 (+)	1284	WP_002983372.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL04_RS02250 (NCTC12062_00444)	-	424705..425061 (-)	357	WP_047235695.1	hypothetical protein	-
DQL04_RS02255 (NCTC12062_00445)	-	425058..425477 (-)	420	WP_002983376.1	HIT family protein	-
DQL04_RS02260 (NCTC12062_00446)	pptA	425549..426274 (+)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL04_RS02265 (NCTC12062_00447)	-	426277..427311 (+)	1035	WP_002994331.1	ABC transporter permease	-
DQL04_RS02270 (NCTC12062_00448)	ccrZ	427375..428166 (+)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL04_RS02275 (NCTC12062_00449)	trmB	428166..428801 (+)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL04_RS02285 (NCTC12062_00451)	rimP	429060..429596 (+)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQL04_RS02290 (NCTC12062_00452)	nusA	429771..430928 (+)	1158	WP_111690726.1	transcription termination factor NusA	-
DQL04_RS02295 (NCTC12062_00453)	rnpM	430944..431240 (+)	297	WP_002983486.1	RNase P modulator RnpM	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1137416 DQL04_RS02260 WP_002983379.1 425549..426274(+) (pptA) [Streptococcus pyogenes strain NCTC12062]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1137416 DQL04_RS02260 WP_002983379.1 425549..426274(+) (pptA) [Streptococcus pyogenes strain NCTC12062]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714