Detailed information NTG1137411

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: DQL04_RS01465
• Genome accession: NZ_LS483340
• Coordinates: 267983..269053 (+)
• Length: 356 a.a.
• NCBI ID: WP_009880666.1
• Uniprot ID: Q54910
• Organism: Streptococcus pyogenes strain NCTC12062
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 262983..274053

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL04_RS01450 (NCTC12062_00291)	amiA	263511..265481 (+)	1971	WP_047235658.1	peptide ABC transporter substrate-binding protein	Regulator
DQL04_RS01455 (NCTC12062_00292)	amiC	265546..267048 (+)	1503	WP_047235659.1	ABC transporter permease	Regulator
DQL04_RS01460 (NCTC12062_00293)	amiD	267048..267974 (+)	927	WP_002986004.1	oligopeptide ABC transporter permease OppC	Regulator
DQL04_RS01465 (NCTC12062_00294)	amiE	267983..269053 (+)	1071	WP_009880666.1	ABC transporter ATP-binding protein	Regulator
DQL04_RS01470 (NCTC12062_00295)	amiF	269046..269969 (+)	924	WP_002986000.1	ABC transporter ATP-binding protein	Regulator
DQL04_RS09605	-	270007..270090 (-)	84	Protein_236	IS3 family transposase	-
DQL04_RS09610	-	270224..270534 (-)	311	Protein_237	IS3 family transposase	-

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 39645.74 Da
• Isoelectric Point: 5.8952

>NTDB_id=1137411 DQL04_RS01465 WP_009880666.1 267983..269053(+) (amiE) [Streptococcus pyogenes strain NCTC12062]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQGLHQKILRKMSQQEEGNV

Nucleotide

• Length: 1071 bp

>NTDB_id=1137411 DQL04_RS01465 WP_009880666.1 267983..269053(+) (amiE) [Streptococcus pyogenes strain NCTC12062]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGGTTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-299)

3D structure

• AlphaFold DB: Q54910

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	76.667	100	0.775
amiE	Streptococcus thermophilus LMG 18311	75.556	100	0.764
amiE	Streptococcus thermophilus LMD-9	75.556	100	0.764
oppD	Streptococcus mutans UA159	56.677	94.663	0.537