Detailed information NTG1137381

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQL34_RS09060
• Genome accession: NZ_LS483339
• Coordinates: 1709386..1710462 (-)
• Length: 358 a.a.
• NCBI ID: WP_172451565.1
• Uniprot ID: A0A2X3UZR3
• Organism: Streptococcus thermophilus strain NCTC12958
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1704386..1715462

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL34_RS09040 (NCTC12958_01903)	-	1705496..1707562 (-)	2067	WP_084829062.1	cation:proton antiporter	-
DQL34_RS09045 (NCTC12958_01904)	-	1707571..1707813 (-)	243	WP_011226461.1	hypothetical protein	-
DQL34_RS09050 (NCTC12958_01905)	-	1707810..1708358 (-)	549	WP_084829063.1	tRNA (mnm(5)s(2)U34)-methyltransferase	-
DQL34_RS09055 (NCTC12958_01906)	-	1708351..1709301 (-)	951	WP_111679688.1	TIGR01212 family radical SAM protein	-
DQL34_RS09060 (NCTC12958_01907)	sepM	1709386..1710462 (-)	1077	WP_172451565.1	SepM family pheromone-processing serine protease	Regulator
DQL34_RS09065 (NCTC12958_01908)	coaD	1710440..1710937 (-)	498	WP_095559436.1	pantetheine-phosphate adenylyltransferase	-
DQL34_RS09070 (NCTC12958_01909)	rsmD	1710971..1711570 (-)	600	Protein_1723	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQL34_RS09075 (NCTC12958_01910)	trxB	1711661..1712614 (-)	954	WP_259700003.1	thioredoxin-disulfide reductase	-
DQL34_RS09080 (NCTC12958_01911)	-	1712647..1712871 (-)	225	WP_084829068.1	DUF4059 family protein	-
DQL34_RS09085 (NCTC12958_01912)	-	1713086..1713829 (-)	744	WP_084829069.1	amino acid ABC transporter ATP-binding protein	-
DQL34_RS09090 (NCTC12958_01913)	-	1713829..1714575 (-)	747	WP_100262472.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 39138.03 Da
• Isoelectric Point: 9.6075

>NTDB_id=1137381 DQL34_RS09060 WP_172451565.1 1709386..1710462(-) (sepM) [Streptococcus thermophilus strain NCTC12958]
MANKTKSKSLLEKMWRIKWRLLSIFTVLFLLFALFFPLNNYYVELPGGAFDTKEVLTVNKKADDSKGSYNFVAVAQTKAT
LALMLYAQFNDFAKLQTAEEATGNYSDEDFMRINQFYMETSQNQAVYQGLTLAGKEVSLEYMGVYVLQVADDSSFKGVLN
IADTVTAVNGKTFDNSTDMIKYVQGLKLGSKVKVTYIRDGKEKTATGKIIKIANGKNGIGIGLTDHTEIKSPENVKFKLD
GVGGPSAGLMFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGAVGDIGGAYLKVKSAADSGADIFFVPNNLVTKEMKKADPD
AKTNYQEAKEAAEKLGTKMKIVPVKTAQEAIDFLKKTK

Nucleotide

• Length: 1077 bp

>NTDB_id=1137381 DQL34_RS09060 WP_172451565.1 1709386..1710462(-) (sepM) [Streptococcus thermophilus strain NCTC12958]
GTGGCAAACAAGACAAAATCTAAATCGCTATTAGAGAAAATGTGGCGTATTAAGTGGCGGTTATTAAGTATTTTTACGGT
ACTTTTCCTCCTTTTTGCCCTCTTTTTCCCGCTCAATAATTACTATGTGGAGCTTCCGGGTGGTGCTTTTGATACCAAGG
AAGTCTTGACAGTGAATAAGAAAGCTGATGATTCTAAGGGCTCCTATAATTTTGTGGCGGTGGCTCAAACCAAGGCGACT
TTGGCCTTGATGCTCTATGCTCAGTTTAATGATTTTGCAAAGCTTCAAACGGCTGAAGAGGCAACTGGAAATTACTCTGA
TGAAGATTTCATGCGCATCAACCAATTTTACATGGAGACTTCTCAAAACCAAGCGGTTTATCAGGGCTTGACTCTGGCTG
GTAAGGAGGTTAGTTTGGAGTATATGGGTGTCTATGTGCTTCAGGTTGCTGATGATTCTAGCTTCAAGGGTGTCCTCAAT
ATTGCTGATACGGTGACGGCTGTTAATGGTAAGACCTTTGATAATTCTACTGACATGATTAAATACGTTCAAGGACTTAA
GCTGGGTTCAAAGGTCAAGGTCACTTATATTAGAGATGGCAAAGAAAAGACTGCTACTGGTAAGATTATTAAGATTGCCA
ATGGCAAAAATGGTATTGGTATCGGCCTAACGGACCATACTGAGATCAAGAGTCCTGAGAATGTTAAGTTTAAACTGGAT
GGTGTCGGTGGGCCAAGTGCTGGTCTTATGTTTACCTTGGCTATTTACGATCAGGTGTCTGGTCAAGACCTCAAGGCTGG
CCGCAAGATTGCTGGTACAGGAACTATTGAAAAAGATGGGGCTGTCGGTGATATCGGTGGGGCCTATCTCAAGGTGAAAT
CTGCGGCTGATAGTGGCGCAGACATTTTCTTCGTGCCAAATAATCTAGTAACTAAGGAAATGAAAAAGGCTGATCCGGAT
GCCAAGACTAATTATCAAGAGGCCAAGGAAGCTGCCGAGAAACTGGGGACCAAGATGAAAATCGTCCCTGTTAAAACAGC
TCAAGAAGCCATTGATTTTTTGAAAAAGACTAAATGA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-206)

3D structure

• AlphaFold DB: A0A2X3UZR3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	62.463	95.251	0.595