Detailed information NTG1137265

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL03_RS06845
• Genome accession: NZ_LS483337
• Coordinates: 1350713..1351438 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12047
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1345713..1356438

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL03_RS06810 (NCTC12047_01351)	rnpM	1345747..1346043 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQL03_RS06815 (NCTC12047_01352)	nusA	1346059..1347216 (-)	1158	WP_002988817.1	transcription termination factor NusA	-
DQL03_RS06820 (NCTC12047_01353)	rimP	1347391..1347927 (-)	537	WP_002983483.1	ribosome maturation factor RimP	-
DQL03_RS06830 (NCTC12047_01355)	trmB	1348186..1348821 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL03_RS06835 (NCTC12047_01356)	ccrZ	1348821..1349612 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL03_RS06840 (NCTC12047_01357)	-	1349676..1350710 (-)	1035	WP_010922583.1	ABC transporter permease	-
DQL03_RS06845 (NCTC12047_01358)	pptA	1350713..1351438 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL03_RS06850 (NCTC12047_01359)	-	1351510..1351929 (+)	420	WP_002983376.1	HIT family protein	-
DQL03_RS06855 (NCTC12047_01360)	-	1351926..1352282 (+)	357	WP_032464516.1	hypothetical protein	-
DQL03_RS06860 (NCTC12047_01361)	brpA	1352393..1353676 (-)	1284	WP_002983372.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL03_RS06865 (NCTC12047_01362)	-	1353685..1354209 (-)	525	WP_020905405.1	GNAT family N-acetyltransferase	-
DQL03_RS06870 (NCTC12047_01363)	tsaE	1354184..1354645 (-)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL03_RS06875 (NCTC12047_01364)	-	1354799..1356259 (-)	1461	WP_012560892.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1137265 DQL03_RS06845 WP_002983379.1 1350713..1351438(-) (pptA) [Streptococcus pyogenes strain NCTC12047]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1137265 DQL03_RS06845 WP_002983379.1 1350713..1351438(-) (pptA) [Streptococcus pyogenes strain NCTC12047]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714