Detailed information NTG1137260

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQL03_RS06030
• Genome accession: NZ_LS483337
• Coordinates: 1188018..1189055 (-)
• Length: 345 a.a.
• NCBI ID: WP_032464469.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12047
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1183018..1194055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL03_RS06005 (NCTC12047_01193)	-	1183022..1183549 (-)	528	WP_002983837.1	Dps family protein	-
DQL03_RS06010 (NCTC12047_01194)	-	1183777..1184403 (+)	627	WP_002983834.1	prepilin peptidase	-
DQL03_RS06015 (NCTC12047_01195)	rlmN	1184485..1185564 (-)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DQL03_RS06020 (NCTC12047_01196)	-	1185568..1186188 (-)	621	WP_231871574.1	YutD family protein	-
DQL03_RS06025 (NCTC12047_01198)	-	1186636..1187613 (-)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
DQL03_RS06030 (NCTC12047_01199)	sepM	1188018..1189055 (-)	1038	WP_032464469.1	SepM family pheromone-processing serine protease	Regulator
DQL03_RS06035 (NCTC12047_01200)	coaD	1189042..1189533 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
DQL03_RS06040 (NCTC12047_01201)	rsmD	1189523..1190062 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQL03_RS06045 (NCTC12047_01202)	asnA	1190185..1191177 (-)	993	WP_032464470.1	aspartate--ammonia ligase	-
DQL03_RS06050 (NCTC12047_01203)	arcC	1191490..1192440 (-)	951	WP_010922501.1	carbamate kinase	-
DQL03_RS06055 (NCTC12047_01204)	-	1192460..1193791 (-)	1332	WP_111674964.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37527.17 Da
• Isoelectric Point: 9.5788

>NTDB_id=1137260 DQL03_RS06030 WP_032464469.1 1188018..1189055(-) (sepM) [Streptococcus pyogenes strain NCTC12047]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGN
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=1137260 DQL03_RS06030 WP_032464469.1 1188018..1189055(-) (sepM) [Streptococcus pyogenes strain NCTC12047]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGCTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAC
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.986	100	0.69