Detailed information NTG1137209

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL08_RS07195
• Genome accession: NZ_LS483336
• Coordinates: 1400807..1401532 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12046
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1395807..1406532

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL08_RS07160 (NCTC12046_01428)	rnpM	1395841..1396137 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQL08_RS07165 (NCTC12046_01429)	nusA	1396153..1397310 (-)	1158	WP_023611711.1	transcription termination factor NusA	-
DQL08_RS07170 (NCTC12046_01430)	rimP	1397485..1398021 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQL08_RS07180 (NCTC12046_01432)	trmB	1398280..1398915 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL08_RS07185 (NCTC12046_01433)	ccrZ	1398915..1399706 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL08_RS07190 (NCTC12046_01434)	-	1399770..1400804 (-)	1035	WP_002994331.1	ABC transporter permease	-
DQL08_RS07195 (NCTC12046_01435)	pptA	1400807..1401532 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL08_RS07200 (NCTC12046_01436)	-	1401604..1402023 (+)	420	WP_002983376.1	HIT family protein	-
DQL08_RS07205 (NCTC12046_01437)	-	1402020..1402376 (+)	357	WP_002983373.1	hypothetical protein	-
DQL08_RS07210 (NCTC12046_01438)	brpA	1402487..1403770 (-)	1284	WP_032467221.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL08_RS07215 (NCTC12046_01439)	-	1403779..1404303 (-)	525	WP_002983369.1	GNAT family N-acetyltransferase	-
DQL08_RS07220 (NCTC12046_01440)	tsaE	1404278..1404739 (-)	462	WP_002983367.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL08_RS07225 (NCTC12046_01441)	-	1404893..1406353 (-)	1461	WP_002983366.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1137209 DQL08_RS07195 WP_002983379.1 1400807..1401532(-) (pptA) [Streptococcus pyogenes strain NCTC12046]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1137209 DQL08_RS07195 WP_002983379.1 1400807..1401532(-) (pptA) [Streptococcus pyogenes strain NCTC12046]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCTTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTTGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714