Detailed information NTG1137154

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL44_RS07980
• Genome accession: NZ_LS483335
• Coordinates: 1497244..1497969 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC8332
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1492244..1502969

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL44_RS07945 (NCTC8332_01601)	rnpM	1492278..1492574 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQL44_RS07950 (NCTC8332_01602)	nusA	1492590..1493747 (-)	1158	WP_002983485.1	transcription termination factor NusA	-
DQL44_RS07955 (NCTC8332_01603)	rimP	1493922..1494458 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQL44_RS07965 (NCTC8332_01605)	trmB	1494717..1495352 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL44_RS07970 (NCTC8332_01606)	ccrZ	1495352..1496143 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL44_RS07975 (NCTC8332_01607)	-	1496207..1497241 (-)	1035	WP_002983381.1	ABC transporter permease	-
DQL44_RS07980 (NCTC8332_01608)	pptA	1497244..1497969 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL44_RS07985 (NCTC8332_01609)	-	1498041..1498460 (+)	420	WP_002983376.1	HIT family protein	-
DQL44_RS07990 (NCTC8332_01610)	-	1498457..1498813 (+)	357	WP_111677437.1	chemotaxis protein	-
DQL44_RS07995 (NCTC8332_01611)	brpA	1498924..1500207 (-)	1284	WP_002983372.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL44_RS08000 (NCTC8332_01612)	-	1500216..1500740 (-)	525	WP_002983369.1	GNAT family N-acetyltransferase	-
DQL44_RS08005 (NCTC8332_01613)	tsaE	1500715..1501176 (-)	462	WP_002983367.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL44_RS08010 (NCTC8332_01614)	-	1501330..1502790 (-)	1461	WP_011106621.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1137154 DQL44_RS07980 WP_002983379.1 1497244..1497969(-) (pptA) [Streptococcus pyogenes strain NCTC8332]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1137154 DQL44_RS07980 WP_002983379.1 1497244..1497969(-) (pptA) [Streptococcus pyogenes strain NCTC8332]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCTTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714