Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   DQL28_RS08825 Genome accession   NZ_LS483334
Coordinates   1750079..1750792 (+) Length   237 a.a.
NCBI ID   WP_111676868.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12050     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1745079..1755792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL28_RS08815 (NCTC12050_01745) treC 1746149..1747777 (-) 1629 WP_111676864.1 alpha,alpha-phosphotrehalase -
  DQL28_RS08820 (NCTC12050_01746) treP 1747844..1749868 (-) 2025 WP_111676866.1 PTS system trehalose-specific EIIBC component -
  DQL28_RS08825 (NCTC12050_01747) treR 1750079..1750792 (+) 714 WP_111676868.1 trehalose operon repressor Regulator
  DQL28_RS08835 - 1751071..1751362 (-) 292 Protein_1650 winged helix-turn-helix transcriptional regulator -
  DQL28_RS08840 (NCTC12050_01748) - 1751598..1752455 (+) 858 WP_111676870.1 VOC family protein -
  DQL28_RS08845 (NCTC12050_01749) yaaA 1752497..1753228 (+) 732 WP_111676872.1 peroxide stress protein YaaA -
  DQL28_RS08850 (NCTC12050_01750) nrdG 1753402..1754016 (-) 615 WP_002982219.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  DQL28_RS08855 (NCTC12050_01751) - 1754016..1754525 (-) 510 WP_111676874.1 GNAT family N-acetyltransferase -
  DQL28_RS08860 (NCTC12050_01752) - 1754534..1755469 (-) 936 WP_111676876.1 Gfo/Idh/MocA family protein -
  DQL28_RS09420 (NCTC12050_01753) - 1755498..1755644 (-) 147 WP_168388750.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27594.75 Da        Isoelectric Point: 9.6307

>NTDB_id=1137102 DQL28_RS08825 WP_111676868.1 1750079..1750792(+) (treR) [Streptococcus pyogenes strain NCTC12050]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIRHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRAK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=1137102 DQL28_RS08825 WP_111676868.1 1750079..1750792(+) (treR) [Streptococcus pyogenes strain NCTC12050]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAGACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACACGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTCTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGAGCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.376

98.734

0.675

Multiple sequence alignment