Detailed information NTG1137073

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL28_RS02165
• Genome accession: NZ_LS483334
• Coordinates: 408293..409018 (+)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12050
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 403293..414018

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL28_RS02135 (NCTC12050_00417)	-	403481..404941 (+)	1461	WP_023609915.1	NCS2 family permease	-
DQL28_RS02140 (NCTC12050_00418)	tsaE	405095..405556 (+)	462	WP_111676180.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL28_RS02145 (NCTC12050_00419)	-	405531..406055 (+)	525	WP_111676182.1	GNAT family N-acetyltransferase	-
DQL28_RS02150 (NCTC12050_00420)	brpA	406064..407338 (+)	1275	WP_111676184.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL28_RS02155 (NCTC12050_00421)	-	407449..407805 (-)	357	WP_038434224.1	hypothetical protein	-
DQL28_RS02160 (NCTC12050_00422)	-	407802..408221 (-)	420	WP_111676186.1	HIT family protein	-
DQL28_RS02165 (NCTC12050_00423)	pptA	408293..409018 (+)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL28_RS02170 (NCTC12050_00424)	-	409021..410055 (+)	1035	WP_002994331.1	ABC transporter permease	-
DQL28_RS02175 (NCTC12050_00425)	ccrZ	410119..410910 (+)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL28_RS02180 (NCTC12050_00426)	trmB	410910..411545 (+)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL28_RS02190 (NCTC12050_00428)	rimP	411804..412340 (+)	537	WP_172450027.1	ribosome maturation factor RimP	-
DQL28_RS02195 (NCTC12050_00429)	nusA	412515..413672 (+)	1158	WP_002988817.1	transcription termination factor NusA	-
DQL28_RS02200 (NCTC12050_00430)	rnpM	413688..413984 (+)	297	WP_002983486.1	RNase P modulator RnpM	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1137073 DQL28_RS02165 WP_002983379.1 408293..409018(+) (pptA) [Streptococcus pyogenes strain NCTC12050]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1137073 DQL28_RS02165 WP_002983379.1 408293..409018(+) (pptA) [Streptococcus pyogenes strain NCTC12050]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACTACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCGATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714