Detailed information NTG1137019

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL30_RS02335
• Genome accession: NZ_LS483333
• Coordinates: 432136..432861 (+)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12048
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 427136..437861

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL30_RS02305 (NCTC12048_00457)	-	427315..428775 (+)	1461	WP_002988645.1	NCS2 family permease	-
DQL30_RS02310 (NCTC12048_00458)	tsaE	428929..429390 (+)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL30_RS02315 (NCTC12048_00459)	-	429365..429889 (+)	525	WP_063811834.1	GNAT family N-acetyltransferase	-
DQL30_RS02320 (NCTC12048_00460)	brpA	429898..431181 (+)	1284	WP_111713633.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL30_RS02325 (NCTC12048_00461)	-	431292..431648 (-)	357	WP_014407784.1	hypothetical protein	-
DQL30_RS02330 (NCTC12048_00462)	-	431645..432064 (-)	420	WP_002983376.1	HIT family protein	-
DQL30_RS02335 (NCTC12048_00463)	pptA	432136..432861 (+)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL30_RS02340 (NCTC12048_00464)	-	432864..433898 (+)	1035	WP_002994331.1	ABC transporter permease	-
DQL30_RS02345 (NCTC12048_00465)	ccrZ	433962..434753 (+)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL30_RS02350 (NCTC12048_00466)	trmB	434753..435388 (+)	636	WP_111684630.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL30_RS02360 (NCTC12048_00468)	rimP	435647..436183 (+)	537	WP_172449889.1	ribosome maturation factor RimP	-
DQL30_RS02365 (NCTC12048_00469)	nusA	436358..437515 (+)	1158	WP_111713634.1	transcription termination factor NusA	-
DQL30_RS02370 (NCTC12048_00470)	rnpM	437531..437827 (+)	297	WP_111713635.1	RNase P modulator RnpM	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1137019 DQL30_RS02335 WP_002983379.1 432136..432861(+) (pptA) [Streptococcus pyogenes strain NCTC12048]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1137019 DQL30_RS02335 WP_002983379.1 432136..432861(+) (pptA) [Streptococcus pyogenes strain NCTC12048]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714