Detailed information NTG1136985

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQM36_RS07170
• Genome accession: NZ_LS483332
• Coordinates: 1378132..1378857 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12696
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1373132..1383857

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM36_RS07135 (NCTC12696_01407)	rnpM	1373166..1373462 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQM36_RS07140 (NCTC12696_01408)	nusA	1373478..1374635 (-)	1158	WP_002994325.1	transcription termination factor NusA	-
DQM36_RS07145 (NCTC12696_01409)	rimP	1374810..1375346 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQM36_RS07155 (NCTC12696_01411)	trmB	1375605..1376240 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQM36_RS07160 (NCTC12696_01412)	ccrZ	1376240..1377031 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQM36_RS07165 (NCTC12696_01413)	-	1377095..1378129 (-)	1035	WP_020837588.1	ABC transporter permease	-
DQM36_RS07170 (NCTC12696_01414)	pptA	1378132..1378857 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQM36_RS07175 (NCTC12696_01415)	-	1378929..1379348 (+)	420	WP_038432458.1	HIT family protein	-
DQM36_RS07180 (NCTC12696_01416)	-	1379345..1379701 (+)	357	WP_002988657.1	hypothetical protein	-
DQM36_RS07185 (NCTC12696_01417)	brpA	1379812..1381086 (-)	1275	WP_020837594.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQM36_RS07190 (NCTC12696_01418)	-	1381095..1381619 (-)	525	WP_009880752.1	GNAT family N-acetyltransferase	-
DQM36_RS07195 (NCTC12696_01419)	tsaE	1381594..1382055 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQM36_RS07200 (NCTC12696_01420)	-	1382209..1383669 (-)	1461	WP_038432459.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1136985 DQM36_RS07170 WP_002983379.1 1378132..1378857(-) (pptA) [Streptococcus pyogenes strain NCTC12696]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1136985 DQM36_RS07170 WP_002983379.1 1378132..1378857(-) (pptA) [Streptococcus pyogenes strain NCTC12696]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714