Detailed information NTG1136927

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL10_RS07245
• Genome accession: NZ_LS483331
• Coordinates: 1427877..1428602 (-)
• Length: 241 a.a.
• NCBI ID: WP_023611908.1
• Uniprot ID: A0A5S4TEK9
• Organism: Streptococcus pyogenes strain NCTC12057
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1422877..1433602

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL10_RS07210 (NCTC12057_01432)	rnpM	1422911..1423207 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQL10_RS07215 (NCTC12057_01433)	nusA	1423223..1424380 (-)	1158	WP_023611711.1	transcription termination factor NusA	-
DQL10_RS07220 (NCTC12057_01434)	rimP	1424555..1425091 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQL10_RS07230 (NCTC12057_01436)	trmB	1425350..1425985 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL10_RS07235 (NCTC12057_01437)	ccrZ	1425985..1426776 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL10_RS07240 (NCTC12057_01438)	-	1426840..1427874 (-)	1035	WP_023611934.1	ABC transporter permease	-
DQL10_RS07245 (NCTC12057_01439)	pptA	1427877..1428602 (-)	726	WP_023611908.1	ABC transporter ATP-binding protein	Regulator
DQL10_RS07250 (NCTC12057_01440)	-	1428674..1429093 (+)	420	WP_023611931.1	HIT family protein	-
DQL10_RS07255 (NCTC12057_01441)	-	1429090..1429446 (+)	357	WP_014407784.1	hypothetical protein	-
DQL10_RS07260 (NCTC12057_01442)	brpA	1429557..1430840 (-)	1284	WP_023611938.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL10_RS07265 (NCTC12057_01443)	-	1430849..1431373 (-)	525	WP_023611919.1	GNAT family N-acetyltransferase	-
DQL10_RS07270 (NCTC12057_01444)	tsaE	1431348..1431809 (-)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL10_RS07275 (NCTC12057_01445)	-	1431963..1433423 (-)	1461	WP_023611933.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26704.78 Da
• Isoelectric Point: 4.4883

>NTDB_id=1136927 DQL10_RS07245 WP_023611908.1 1427877..1428602(-) (pptA) [Streptococcus pyogenes strain NCTC12057]
MLNIKNLTGGYYNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1136927 DQL10_RS07245 WP_023611908.1 1427877..1428602(-) (pptA) [Streptococcus pyogenes strain NCTC12057]
ATGTTAAACATTAAAAATCTAACAGGAGGATATTACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A5S4TEK9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714