Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   DQL27_RS08440 Genome accession   NZ_LS483329
Coordinates   1670806..1671519 (+) Length   237 a.a.
NCBI ID   WP_032464617.1    Uniprot ID   A0A9X8T0Q6
Organism   Streptococcus pyogenes strain NCTC12058     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1665806..1676519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL27_RS08430 (NCTC12058_01668) treC 1666875..1668503 (-) 1629 WP_053308668.1 alpha,alpha-phosphotrehalase -
  DQL27_RS08435 (NCTC12058_01669) treP 1668571..1670595 (-) 2025 WP_111711507.1 PTS system trehalose-specific EIIBC component -
  DQL27_RS08440 (NCTC12058_01670) treR 1670806..1671519 (+) 714 WP_032464617.1 trehalose operon repressor Regulator
  DQL27_RS08450 (NCTC12058_01671) - 1671798..1672135 (-) 338 Protein_1566 winged helix-turn-helix transcriptional regulator -
  DQL27_RS08455 (NCTC12058_01672) - 1672322..1673179 (+) 858 WP_111711508.1 VOC family protein -
  DQL27_RS08460 (NCTC12058_01673) yaaA 1673221..1673952 (+) 732 WP_111711509.1 peroxide stress protein YaaA -
  DQL27_RS08465 (NCTC12058_01674) nrdG 1674126..1674740 (-) 615 WP_021775544.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  DQL27_RS08470 (NCTC12058_01675) - 1674755..1675249 (-) 495 WP_014407930.1 GNAT family N-acetyltransferase -
  DQL27_RS08475 (NCTC12058_01676) - 1675258..1676193 (-) 936 WP_111711510.1 Gfo/Idh/MocA family protein -
  DQL27_RS09050 (NCTC12058_01677) - 1676222..1676368 (-) 147 WP_011106921.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27661.89 Da        Isoelectric Point: 9.7425

>NTDB_id=1136822 DQL27_RS08440 WP_032464617.1 1670806..1671519(+) (treR) [Streptococcus pyogenes strain NCTC12058]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFRKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=1136822 DQL27_RS08440 WP_032464617.1 1670806..1671519(+) (treR) [Streptococcus pyogenes strain NCTC12058]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAAGCATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTCGCAAAAACAGCTTGGTCTGGCGTGTTACACGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCTCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTCTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.803

98.734

0.679

Multiple sequence alignment