Detailed information NTG1136816

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL27_RS06895
• Genome accession: NZ_LS483329
• Coordinates: 1342379..1343104 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12058
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1337379..1348104

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL27_RS06860 (NCTC12058_01366)	rnpM	1337413..1337709 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQL27_RS06865 (NCTC12058_01367)	nusA	1337725..1338882 (-)	1158	WP_002983485.1	transcription termination factor NusA	-
DQL27_RS06870 (NCTC12058_01368)	rimP	1339057..1339593 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQL27_RS06880 (NCTC12058_01370)	trmB	1339852..1340487 (-)	636	WP_111711459.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL27_RS06885 (NCTC12058_01371)	ccrZ	1340487..1341278 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL27_RS06890 (NCTC12058_01372)	-	1341342..1342376 (-)	1035	WP_031577431.1	ABC transporter permease	-
DQL27_RS06895 (NCTC12058_01373)	pptA	1342379..1343104 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL27_RS06900 (NCTC12058_01374)	-	1343176..1343595 (+)	420	WP_002983376.1	HIT family protein	-
DQL27_RS06905 (NCTC12058_01375)	-	1343592..1343948 (+)	357	WP_031488470.1	hypothetical protein	-
DQL27_RS06910 (NCTC12058_01376)	brpA	1344059..1345342 (-)	1284	WP_031488469.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL27_RS06915 (NCTC12058_01377)	-	1345351..1345875 (-)	525	WP_031488468.1	GNAT family N-acetyltransferase	-
DQL27_RS06920 (NCTC12058_01378)	tsaE	1345850..1346311 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL27_RS06925 (NCTC12058_01379)	-	1346465..1347925 (-)	1461	WP_031488467.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1136816 DQL27_RS06895 WP_002983379.1 1342379..1343104(-) (pptA) [Streptococcus pyogenes strain NCTC12058]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1136816 DQL27_RS06895 WP_002983379.1 1342379..1343104(-) (pptA) [Streptococcus pyogenes strain NCTC12058]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714