Detailed information NTG1136796

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQL27_RS02360
• Genome accession: NZ_LS483329
• Coordinates: 431987..433033 (+)
• Length: 348 a.a.
• NCBI ID: WP_111711349.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12058
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 426987..438033

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL27_RS02335 (NCTC12058_00460)	-	427251..428582 (+)	1332	WP_030126384.1	dipeptidase	-
DQL27_RS02340 (NCTC12058_00461)	arcC	428602..429552 (+)	951	WP_010922501.1	carbamate kinase	-
DQL27_RS02345 (NCTC12058_00462)	asnA	429865..430857 (+)	993	WP_002983817.1	aspartate--ammonia ligase	-
DQL27_RS02350 (NCTC12058_00463)	rsmD	430980..431519 (+)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQL27_RS02355 (NCTC12058_00464)	coaD	431509..432000 (+)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
DQL27_RS02360 (NCTC12058_00465)	sepM	431987..433033 (+)	1047	WP_111711349.1	SepM family pheromone-processing serine protease	Regulator
DQL27_RS02365 (NCTC12058_00466)	-	433455..434432 (+)	978	WP_031577505.1	LacI family DNA-binding transcriptional regulator	-
DQL27_RS02370 (NCTC12058_00467)	-	434880..435500 (+)	621	WP_002992791.1	YutD family protein	-
DQL27_RS02375 (NCTC12058_00468)	rlmN	435504..436583 (+)	1080	WP_031488529.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DQL27_RS02380 (NCTC12058_00469)	-	436665..437291 (-)	627	WP_002983834.1	prepilin peptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 37840.57 Da
• Isoelectric Point: 9.7472

>NTDB_id=1136796 DQL27_RS02360 WP_111711349.1 431987..433033(+) (sepM) [Streptococcus pyogenes strain NCTC12058]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAG
LMFTLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEA
KRAAKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1047 bp

>NTDB_id=1136796 DQL27_RS02360 WP_111711349.1 431987..433033(+) (sepM) [Streptococcus pyogenes strain NCTC12058]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTATTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTCTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGAAAAATGGGATTGGCATTG
CCTTGACTGATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGT
CTAATGTTTACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAAC
TATTGGCAAGGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATA
TATTTTTTGTTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCC
AAACGGGCAGCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCG
CAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (236-312)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.678	100	0.687