Detailed information NTG1136702

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL07_RS06950
• Genome accession: NZ_LS483327
• Coordinates: 1344333..1345058 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12069
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1339333..1350058

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL07_RS06915 (NCTC12069_01363)	rnpM	1339367..1339663 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQL07_RS06920 (NCTC12069_01364)	nusA	1339679..1340836 (-)	1158	WP_002994325.1	transcription termination factor NusA	-
DQL07_RS06925 (NCTC12069_01365)	rimP	1341011..1341547 (-)	537	WP_172451336.1	ribosome maturation factor RimP	-
DQL07_RS06935 (NCTC12069_01367)	trmB	1341806..1342441 (-)	636	WP_011184863.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL07_RS06940 (NCTC12069_01368)	ccrZ	1342441..1343232 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL07_RS06945 (NCTC12069_01369)	-	1343296..1344330 (-)	1035	WP_002994331.1	ABC transporter permease	-
DQL07_RS06950 (NCTC12069_01370)	pptA	1344333..1345058 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL07_RS06955 (NCTC12069_01371)	-	1345130..1345549 (+)	420	WP_002983376.1	HIT family protein	-
DQL07_RS06960 (NCTC12069_01372)	-	1345546..1345902 (+)	357	WP_002988657.1	hypothetical protein	-
DQL07_RS06965 (NCTC12069_01373)	brpA	1346013..1347296 (-)	1284	WP_111702912.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL07_RS06970 (NCTC12069_01374)	-	1347305..1347829 (-)	525	WP_111702913.1	GNAT family N-acetyltransferase	-
DQL07_RS06975 (NCTC12069_01375)	tsaE	1347804..1348265 (-)	462	WP_002983367.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL07_RS06980 (NCTC12069_01376)	-	1348419..1349879 (-)	1461	WP_023609915.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1136702 DQL07_RS06950 WP_002983379.1 1344333..1345058(-) (pptA) [Streptococcus pyogenes strain NCTC12069]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1136702 DQL07_RS06950 WP_002983379.1 1344333..1345058(-) (pptA) [Streptococcus pyogenes strain NCTC12069]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714