Detailed information NTG1136631

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL59_RS05880
• Genome accession: NZ_LS483326
• Coordinates: 1145781..1146506 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12045
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1140781..1151506

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL59_RS05845 (NCTC12045_01160)	rnpM	1140815..1141111 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQL59_RS05850 (NCTC12045_01161)	nusA	1141127..1142284 (-)	1158	WP_111681243.1	transcription termination factor NusA	-
DQL59_RS05855 (NCTC12045_01162)	rimP	1142459..1142995 (-)	537	WP_002983483.1	ribosome maturation factor RimP	-
DQL59_RS05865 (NCTC12045_01164)	trmB	1143254..1143889 (-)	636	WP_111681244.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL59_RS05870 (NCTC12045_01165)	ccrZ	1143889..1144680 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL59_RS05875 (NCTC12045_01166)	-	1144744..1145778 (-)	1035	WP_111681245.1	ABC transporter permease	-
DQL59_RS05880 (NCTC12045_01167)	pptA	1145781..1146506 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL59_RS05885 (NCTC12045_01168)	-	1146578..1146997 (+)	420	WP_002983376.1	HIT family protein	-
DQL59_RS05890 (NCTC12045_01169)	-	1146994..1147350 (+)	357	WP_031488470.1	hypothetical protein	-
DQL59_RS05895 (NCTC12045_01170)	brpA	1147461..1148744 (-)	1284	WP_031488469.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL59_RS05900 (NCTC12045_01171)	-	1148753..1149277 (-)	525	WP_111681246.1	GNAT family N-acetyltransferase	-
DQL59_RS05905 (NCTC12045_01172)	tsaE	1149252..1149713 (-)	462	WP_030126320.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL59_RS05910 (NCTC12045_01173)	-	1149867..1151327 (-)	1461	WP_012560892.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1136631 DQL59_RS05880 WP_002983379.1 1145781..1146506(-) (pptA) [Streptococcus pyogenes strain NCTC12045]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1136631 DQL59_RS05880 WP_002983379.1 1145781..1146506(-) (pptA) [Streptococcus pyogenes strain NCTC12045]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714