Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DQL79_RS11035 Genome accession   NZ_LS483324
Coordinates   2119981..2120697 (+) Length   238 a.a.
NCBI ID   WP_111763591.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NCTC10344     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2114981..2125697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL79_RS11005 (NCTC10344_02067) - 2115201..2115827 (+) 627 WP_000522384.1 nitroreductase family protein -
  DQL79_RS11010 (NCTC10344_02068) - 2116188..2116973 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  DQL79_RS15050 hld 2117569..2117649 (-) 81 WP_000046022.1 delta-hemolysin -
  DQL79_RS11020 (NCTC10344_02070) agrB 2117939..2118508 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  DQL79_RS11025 (NCTC10344_02071) agrD 2118505..2118645 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  DQL79_RS11030 (NCTC10344_02072) agrC 2118670..2119962 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  DQL79_RS11035 (NCTC10344_02073) agrA 2119981..2120697 (+) 717 WP_111763591.1 quorum-sensing response regulator AgrA Regulator
  DQL79_RS11040 - 2120769..2120878 (+) 110 Protein_2056 hypothetical protein -
  DQL79_RS11045 (NCTC10344_02074) - 2121066..2122025 (-) 960 WP_001253302.1 carbohydrate kinase family protein -
  DQL79_RS11050 (NCTC10344_02075) - 2122022..2123506 (-) 1485 WP_000141426.1 sucrose-6-phosphate hydrolase -
  DQL79_RS11055 (NCTC10344_02076) - 2123655..2124605 (-) 951 WP_000790324.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.86 Da        Isoelectric Point: 6.0927

>NTDB_id=1136541 DQL79_RS11035 WP_111763591.1 2119981..2120697(+) (agrA) [Staphylococcus aureus strain NCTC10344]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIAYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1136541 DQL79_RS11035 WP_111763591.1 2119981..2120697(+) (agrA) [Staphylococcus aureus strain NCTC10344]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGCCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.16

100

0.992

Multiple sequence alignment