Detailed information NTG1136415

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL05_RS02140
• Genome accession: NZ_LS483322
• Coordinates: 405019..405744 (+)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12066
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 400019..410744

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL05_RS02110 (NCTC12066_00418)	-	400198..401658 (+)	1461	WP_002988645.1	NCS2 family permease	-
DQL05_RS02115 (NCTC12066_00419)	tsaE	401812..402273 (+)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL05_RS02120 (NCTC12066_00420)	-	402248..402772 (+)	525	WP_002988650.1	GNAT family N-acetyltransferase	-
DQL05_RS02125 (NCTC12066_00421)	brpA	402781..404064 (+)	1284	WP_002983372.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL05_RS02130 (NCTC12066_00422)	-	404175..404531 (-)	357	WP_002988657.1	hypothetical protein	-
DQL05_RS02135 (NCTC12066_00423)	-	404528..404947 (-)	420	WP_002988659.1	HIT family protein	-
DQL05_RS02140 (NCTC12066_00424)	pptA	405019..405744 (+)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL05_RS02145 (NCTC12066_00425)	-	405747..406781 (+)	1035	WP_002988663.1	ABC transporter permease	-
DQL05_RS02150 (NCTC12066_00426)	ccrZ	406845..407636 (+)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL05_RS02155 (NCTC12066_00427)	trmB	407636..408271 (+)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL05_RS02165 (NCTC12066_00429)	rimP	408531..409067 (+)	537	WP_030127299.1	ribosome maturation factor RimP	-
DQL05_RS02170 (NCTC12066_00430)	nusA	409242..410399 (+)	1158	WP_109828786.1	transcription termination factor NusA	-
DQL05_RS02175 (NCTC12066_00431)	rnpM	410415..410711 (+)	297	WP_002983486.1	RNase P modulator RnpM	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1136415 DQL05_RS02140 WP_002983379.1 405019..405744(+) (pptA) [Streptococcus pyogenes strain NCTC12066]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1136415 DQL05_RS02140 WP_002983379.1 405019..405744(+) (pptA) [Streptococcus pyogenes strain NCTC12066]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714