Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DQL75_RS10760 Genome accession   NZ_LS483317
Coordinates   2095257..2095973 (+) Length   238 a.a.
NCBI ID   WP_031793408.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NCTC5663     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2090257..2100973
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL75_RS10730 (NCTC5663_02027) - 2090511..2091137 (+) 627 WP_000522384.1 nitroreductase family protein -
  DQL75_RS10735 (NCTC5663_02028) - 2091461..2092246 (+) 786 WP_086153164.1 carbon-nitrogen family hydrolase -
  DQL75_RS10740 hld 2092845..2092925 (-) 81 WP_000046022.1 delta-hemolysin -
  DQL75_RS10745 (NCTC5663_02030) - 2093216..2093779 (+) 564 WP_001105699.1 accessory gene regulator AgrB -
  DQL75_RS10750 (NCTC5663_02031) agrD 2093782..2093925 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  DQL75_RS10755 (NCTC5663_02032) agrC 2093955..2095238 (+) 1284 WP_000447894.1 quorum-sensing sensor histidine kinase AgrC -
  DQL75_RS10760 (NCTC5663_02033) agrA 2095257..2095973 (+) 717 WP_031793408.1 quorum-sensing response regulator AgrA Regulator
  DQL75_RS10765 - 2096045..2096152 (+) 108 WP_041204320.1 hypothetical protein -
  DQL75_RS10770 (NCTC5663_02034) - 2096340..2097299 (-) 960 WP_111762503.1 carbohydrate kinase family protein -
  DQL75_RS10775 (NCTC5663_02035) - 2097296..2098780 (-) 1485 WP_111762504.1 sucrose-6-phosphate hydrolase -
  DQL75_RS10780 (NCTC5663_02036) - 2098929..2099879 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27935.99 Da        Isoelectric Point: 6.0927

>NTDB_id=1136170 DQL75_RS10760 WP_031793408.1 2095257..2095973(+) (agrA) [Staphylococcus aureus strain NCTC5663]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVMSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1136170 DQL75_RS10760 WP_031793408.1 2095257..2095973(+) (agrA) [Staphylococcus aureus strain NCTC5663]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTATGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment