Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   DQL73_RS00240 Genome accession   NZ_LS483316
Coordinates   49612..50973 (-) Length   453 a.a.
NCBI ID   WP_001631036.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NCTC13395     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 41242..55395 49612..50973 within 0


Gene organization within MGE regions


Location: 41242..55395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL73_RS00200 (NCTC13395_00038) mecA 41242..43251 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  DQL73_RS00205 (NCTC13395_00039) - 43348..44334 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  DQL73_RS00210 (NCTC13395_00040) - 44324..44566 (+) 243 Protein_35 type I restriction enzyme endonuclease domain-containing protein -
  DQL73_RS00215 (NCTC13395_00041) - 44557..46167 (-) 1611 Protein_36 IS1182 family transposase -
  DQL73_RS00220 (NCTC13395_00042) - 46216..46722 (-) 507 WP_061734628.1 DUF1643 domain-containing protein -
  DQL73_RS00225 (NCTC13395_00043) - 46738..47049 (-) 312 WP_001631033.1 DUF960 domain-containing protein -
  DQL73_RS00230 (NCTC13395_00045) - 47136..47486 (-) 351 WP_061734627.1 SAUGI family uracil-DNA glycosylase inhibitor -
  DQL73_RS00235 (NCTC13395_00046) ccrB 47987..49615 (-) 1629 WP_001631035.1 cassette chromosome recombinase CcrB Machinery gene
  DQL73_RS00240 (NCTC13395_00047) ccrA 49612..50973 (-) 1362 WP_001631036.1 cassette chromosome recombinase CcrA Machinery gene
  DQL73_RS00245 (NCTC13395_00048) - 51160..51789 (-) 630 Protein_42 hypothetical protein -
  DQL73_RS00250 - 51798..52136 (+) 339 Protein_43 recombinase family protein -
  DQL73_RS00255 (NCTC13395_00050) - 52248..52607 (-) 360 WP_001631039.1 hypothetical protein -
  DQL73_RS00260 (NCTC13395_00051) - 52814..53140 (+) 327 WP_000391495.1 ArsR/SmtB family transcription factor -
  DQL73_RS00270 (NCTC13395_00053) - 53470..55395 (+) 1926 WP_002485723.1 heavy metal translocating P-type ATPase -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 53316.45 Da        Isoelectric Point: 9.8596

>NTDB_id=1136093 DQL73_RS00240 WP_001631036.1 49612..50973(-) (ccrA) [Staphylococcus aureus strain NCTC13395]
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=1136093 DQL73_RS00240 WP_001631036.1 49612..50973(-) (ccrA) [Staphylococcus aureus strain NCTC13395]
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(168-248)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

54.628

97.792

0.534
  ccrA Staphylococcus aureus N315

50.564

97.792

0.494

Multiple sequence alignment