Detailed information NTG1136057

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQL11_RS02215
• Genome accession: NZ_LS483315
• Coordinates: 419320..420045 (+)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12059
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 414320..425045

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL11_RS02185 (NCTC12059_00432)	-	414499..415959 (+)	1461	WP_031488467.1	NCS2 family permease	-
DQL11_RS02190 (NCTC12059_00433)	tsaE	416113..416574 (+)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQL11_RS02195 (NCTC12059_00434)	-	416549..417073 (+)	525	WP_031488468.1	GNAT family N-acetyltransferase	-
DQL11_RS02200 (NCTC12059_00435)	brpA	417082..418365 (+)	1284	WP_111704550.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQL11_RS02205 (NCTC12059_00436)	-	418476..418832 (-)	357	WP_031488470.1	hypothetical protein	-
DQL11_RS02210 (NCTC12059_00437)	-	418829..419248 (-)	420	WP_002983376.1	HIT family protein	-
DQL11_RS02215 (NCTC12059_00438)	pptA	419320..420045 (+)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQL11_RS02220 (NCTC12059_00439)	-	420048..421082 (+)	1035	WP_031577431.1	ABC transporter permease	-
DQL11_RS02225 (NCTC12059_00440)	ccrZ	421146..421937 (+)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQL11_RS02230 (NCTC12059_00441)	trmB	421937..422572 (+)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQL11_RS02240 (NCTC12059_00443)	rimP	422831..423367 (+)	537	WP_002983483.1	ribosome maturation factor RimP	-
DQL11_RS02245 (NCTC12059_00444)	nusA	423542..424699 (+)	1158	WP_002988817.1	transcription termination factor NusA	-
DQL11_RS02250 (NCTC12059_00445)	rnpM	424715..425011 (+)	297	WP_002983486.1	RNase P modulator RnpM	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1136057 DQL11_RS02215 WP_002983379.1 419320..420045(+) (pptA) [Streptococcus pyogenes strain NCTC12059]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1136057 DQL11_RS02215 WP_002983379.1 419320..420045(+) (pptA) [Streptococcus pyogenes strain NCTC12059]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714