Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DQL90_RS10635 Genome accession   NZ_LS483314
Coordinates   2060452..2061168 (+) Length   238 a.a.
NCBI ID   WP_111688666.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NCTC3761     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2055452..2066168
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL90_RS10605 (NCTC3761_02007) - 2055672..2056298 (+) 627 WP_000522384.1 nitroreductase family protein -
  DQL90_RS10610 (NCTC3761_02008) - 2056659..2057444 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  DQL90_RS14630 hld 2058040..2058120 (-) 81 WP_000046022.1 delta-hemolysin -
  DQL90_RS10620 (NCTC3761_02010) agrB 2058410..2058979 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  DQL90_RS10625 (NCTC3761_02011) agrD 2058976..2059116 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  DQL90_RS10630 (NCTC3761_02012) agrC 2059141..2060433 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  DQL90_RS10635 (NCTC3761_02013) agrA 2060452..2061168 (+) 717 WP_111688666.1 quorum-sensing response regulator AgrA Regulator
  DQL90_RS10640 - 2061240..2061349 (+) 110 Protein_1984 hypothetical protein -
  DQL90_RS10645 (NCTC3761_02014) - 2061537..2062496 (-) 960 WP_001253302.1 carbohydrate kinase family protein -
  DQL90_RS10650 (NCTC3761_02015) - 2062493..2063977 (-) 1485 WP_042727666.1 sucrose-6-phosphate hydrolase -
  DQL90_RS10655 (NCTC3761_02016) - 2064126..2065076 (-) 951 WP_000790324.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27946.91 Da        Isoelectric Point: 6.0927

>NTDB_id=1136031 DQL90_RS10635 WP_111688666.1 2060452..2061168(+) (agrA) [Staphylococcus aureus strain NCTC3761]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELNYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1136031 DQL90_RS10635 WP_111688666.1 2060452..2061168(+) (agrA) [Staphylococcus aureus strain NCTC3761]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTAACTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.16

100

0.992

Multiple sequence alignment