Detailed information NTG1135971

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DQL89_RS05285
• Genome accession: NZ_LS483313
• Coordinates: 1155153..1156196 (+)
• Length: 347 a.a.
• NCBI ID: WP_002481663.1
• Uniprot ID: -
• Organism: Staphylococcus simulans strain NCTC11046
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1150153..1161196

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL89_RS05260 (NCTC11046_01079)	-	1151156..1151875 (+)	720	WP_023015863.1	type 1 glutamine amidotransferase	-
DQL89_RS05265 (NCTC11046_01080)	-	1151958..1152944 (-)	987	WP_002481667.1	FUSC family protein	-
DQL89_RS05270 (NCTC11046_01081)	map	1153164..1153928 (+)	765	WP_060803962.1	type I methionyl aminopeptidase	-
DQL89_RS05275 (NCTC11046_01082)	-	1154044..1154439 (+)	396	WP_002481665.1	hypothetical protein	-
DQL89_RS05280 (NCTC11046_01083)	liaF	1154455..1155156 (+)	702	WP_002481664.1	cell wall-active antibiotics response protein LiaF	-
DQL89_RS05285 (NCTC11046_01084)	vraS	1155153..1156196 (+)	1044	WP_002481663.1	sensor histidine kinase	Regulator
DQL89_RS05290 (NCTC11046_01085)	vraR	1156186..1156815 (+)	630	WP_002481662.1	response regulator transcription factor	Regulator
DQL89_RS05295 (NCTC11046_01086)	-	1156886..1157464 (-)	579	WP_002481661.1	beta-class carbonic anhydrase	-
DQL89_RS05300 (NCTC11046_01087)	-	1157672..1158748 (-)	1077	WP_002481660.1	YihY/virulence factor BrkB family protein	-
DQL89_RS05305 (NCTC11046_01088)	-	1158879..1159169 (-)	291	WP_002481659.1	hypothetical protein	-
DQL89_RS05310 (NCTC11046_01089)	-	1159177..1159641 (-)	465	WP_023015860.1	low molecular weight protein-tyrosine-phosphatase	-
DQL89_RS05315 (NCTC11046_01090)	-	1159865..1160071 (+)	207	WP_002481657.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39897.15 Da
• Isoelectric Point: 4.8944

>NTDB_id=1135971 DQL89_RS05285 WP_002481663.1 1155153..1156196(+) (vraS) [Staphylococcus simulans strain NCTC11046]
MNHYIRAIGSMLILNYSILAIFFFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNEQNDWIKT
QIEHSIEGEVVGINDQNIELYQETLDIYHTLVPLNQELHRLRIKTQDLTNETYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESPLEPPLDQQIPTLEKMVQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGTKLTIDLFNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEENDGD

Nucleotide

• Length: 1044 bp

>NTDB_id=1135971 DQL89_RS05285 WP_002481663.1 1155153..1156196(+) (vraS) [Staphylococcus simulans strain NCTC11046]
ATGAACCACTATATCAGAGCCATCGGTTCGATGCTGATATTGAACTATAGTATTTTAGCGATTTTCTTTTTTATAGACAA
AGTATTCGTCAACATCATCTACTTTCAAGGAATGTTTTACACGCAGATTTTCGGCATTCCTGTTTTCTTATTTTTAAATA
TTATAGTGATTTTGATGAGTATTATTGTTGGTTCTGTGTTAGCGTATAAAGTGAACGAACAAAATGATTGGATTAAAACA
CAAATTGAACATTCCATTGAAGGGGAAGTTGTCGGTATTAATGATCAAAATATCGAACTCTACCAAGAAACTTTGGATAT
CTATCATACACTTGTGCCATTAAACCAAGAATTACATCGACTACGTATTAAAACACAAGATTTGACCAACGAAACATATA
ATTTAAATGACGTTAAAGTGAAGAAAATTATAGAAGATGAACGCCAGCGTTTAGCTAGGGAATTGCATGATTCAGTTAGT
CAGCAATTATTTGCGGCAAGTATGATGTTATCGGCGATTAAGGAATCACCACTTGAACCGCCACTTGATCAGCAAATTCC
AACACTAGAAAAGATGGTCCAAGATTCGCAACTAGAAATGCGTGCATTGTTATTACATTTAAGACCGCTTGGCTTAAAAG
ATCGCTCACTTGGGGAAGGAATTAAAGATCTTGTTGTGGACTTACAAAAGAAAGTGCCTATGAAAGTAGTTTATGATATT
GAAGACTTTGAGGTACCAAAAGGCATAGAAGATCATTTATTCCGTATCACCCAAGAAGGGATTTCCAATACACTGCGACA
TGCAGAAGGCACAAAATTAACGATAGATTTATTTAATAAAGATGATTATCTGTTATTGCGTATTCAAGATGATGGTAAAG
GCTTTGATGTAGATGAAAAAATGGAGAAAAGCTATGGATTGAAGAATATGCGAGAGCGAGCATTAGAAATCGGGGCAACA
CTGCATATTGTTTCTTTGCCTGGGGCAGGGACAAGAATTGAAGTGAAGGCTCCATTGAATAAGGAGGAAAATGATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	86.167	100	0.862