Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DQL83_RS11280 Genome accession   NZ_LS483311
Coordinates   2135918..2136634 (+) Length   238 a.a.
NCBI ID   WP_111724429.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NCTC6136     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2130918..2141634
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL83_RS11250 (NCTC6136_02108) - 2131139..2131765 (+) 627 WP_000522384.1 nitroreductase family protein -
  DQL83_RS11255 (NCTC6136_02109) - 2132125..2132910 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  DQL83_RS15340 hld 2133507..2133587 (-) 81 WP_000046022.1 delta-hemolysin -
  DQL83_RS11265 (NCTC6136_02111) - 2133877..2134440 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  DQL83_RS11270 (NCTC6136_02112) agrD 2134443..2134586 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  DQL83_RS11275 (NCTC6136_02113) agrC 2134616..2135899 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  DQL83_RS11280 (NCTC6136_02114) agrA 2135918..2136634 (+) 717 WP_111724429.1 quorum-sensing response regulator AgrA Regulator
  DQL83_RS11285 - 2136714..2136823 (+) 110 Protein_2104 hypothetical protein -
  DQL83_RS11290 (NCTC6136_02115) - 2137011..2137970 (-) 960 WP_001253314.1 carbohydrate kinase family protein -
  DQL83_RS11295 (NCTC6136_02116) - 2137967..2139451 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  DQL83_RS11300 (NCTC6136_02117) - 2139600..2140550 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27932.93 Da        Isoelectric Point: 6.3001

>NTDB_id=1135925 DQL83_RS11280 WP_111724429.1 2135918..2136634(+) (agrA) [Staphylococcus aureus strain NCTC6136]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDNPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1135925 DQL83_RS11280 WP_111724429.1 2135918..2136634(+) (agrA) [Staphylococcus aureus strain NCTC6136]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATAATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTTAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.16

100

0.992

Multiple sequence alignment