Detailed information NTG1135845

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: DQL85_RS13825
• Genome accession: NZ_LS483308
• Coordinates: 2658488..2659375 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain NCTC13137
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2653488..2664375

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL85_RS13790	-	2653516..2653599 (+)	84	WP_031797553.1	hypothetical protein	-
DQL85_RS13795 (NCTC13137_02565)	-	2653707..2654204 (-)	498	WP_001065267.1	glutathione peroxidase	-
DQL85_RS13800	-	2654214..2654474 (-)	261	WP_001789910.1	hypothetical protein	-
DQL85_RS13810	-	2654856..2654969 (-)	114	WP_011447078.1	hypothetical protein	-
DQL85_RS13815 (NCTC13137_02566)	-	2655628..2657628 (-)	2001	WP_000776751.1	ABC transporter permease	-
DQL85_RS13820 (NCTC13137_02567)	-	2657625..2658380 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
DQL85_RS13825 (NCTC13137_02568)	braS	2658488..2659375 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
DQL85_RS13830 (NCTC13137_02569)	braR	2659386..2660051 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
DQL85_RS13835 (NCTC13137_02570)	-	2660077..2660277 (-)	201	WP_000604728.1	hypothetical protein	-
DQL85_RS13840 (NCTC13137_02571)	-	2660475..2661899 (+)	1425	WP_000953744.1	alkaline phosphatase	-
DQL85_RS14540 (NCTC13137_02572)	-	2661959..2662060 (-)	102	WP_000731972.1	SE2200 family small protein	-
DQL85_RS13850 (NCTC13137_02573)	-	2662182..2662637 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
DQL85_RS13855 (NCTC13137_02574)	-	2662882..2663643 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1135845 DQL85_RS13825 WP_000143419.1 2658488..2659375(-) (braS) [Staphylococcus aureus strain NCTC13137]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1135845 DQL85_RS13825 WP_000143419.1 2658488..2659375(-) (braS) [Staphylococcus aureus strain NCTC13137]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997