Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DQL85_RS10585 Genome accession   NZ_LS483308
Coordinates   2047514..2048245 (+) Length   243 a.a.
NCBI ID   WP_111743882.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NCTC13137     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2042514..2053245
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL85_RS10555 (NCTC13137_01973) - 2042733..2043359 (+) 627 WP_000522384.1 nitroreductase family protein -
  DQL85_RS10560 (NCTC13137_01974) - 2043720..2044505 (+) 786 WP_000867949.1 carbon-nitrogen family hydrolase -
  DQL85_RS14525 hld 2045102..2045182 (-) 81 WP_000046022.1 delta-hemolysin -
  DQL85_RS10570 (NCTC13137_01976) agrB 2045472..2046041 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  DQL85_RS10575 (NCTC13137_01977) agrD 2046038..2046178 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  DQL85_RS10580 (NCTC13137_01978) agrC 2046203..2047495 (+) 1293 WP_172449595.1 quorum-sensing sensor histidine kinase AgrC -
  DQL85_RS10585 (NCTC13137_01979) agrA 2047514..2048245 (+) 732 WP_111743882.1 quorum-sensing response regulator AgrA Regulator
  DQL85_RS10590 - 2048309..2048418 (+) 110 Protein_1968 hypothetical protein -
  DQL85_RS10595 (NCTC13137_01980) - 2048606..2049565 (-) 960 WP_006190739.1 carbohydrate kinase family protein -
  DQL85_RS10600 (NCTC13137_01981) - 2049562..2051046 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  DQL85_RS10605 (NCTC13137_01982) - 2051195..2052145 (-) 951 WP_006190740.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 28594.64 Da        Isoelectric Point: 6.3009

>NTDB_id=1135841 DQL85_RS10585 WP_111743882.1 2047514..2048245(+) (agrA) [Staphylococcus aureus strain NCTC13137]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKYNN
IIR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=1135841 DQL85_RS10585 WP_111743882.1 2047514..2048245(+) (agrA) [Staphylococcus aureus strain NCTC13137]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTTAGAAACGTTAAAAAATATAATAAT
ATAATAAGATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-241)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.578

97.531

0.971

Multiple sequence alignment