Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   DQL78_RS11240 Genome accession   NZ_LS483306
Coordinates   2226669..2228486 (-) Length   605 a.a.
NCBI ID   WP_016250662.1    Uniprot ID   -
Organism   Enterococcus cecorum strain NCTC12421     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2221669..2233486
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL78_RS11210 (NCTC12421_02297) - 2222732..2222950 (+) 219 WP_016250668.1 hypothetical protein -
  DQL78_RS12625 (NCTC12421_02298) - 2223260..2223571 (+) 312 WP_016250667.1 helix-turn-helix transcriptional regulator -
  DQL78_RS11220 (NCTC12421_02299) - 2223543..2224103 (+) 561 WP_016250666.1 hypothetical protein -
  DQL78_RS11225 (NCTC12421_02300) - 2224255..2225142 (+) 888 WP_016250665.1 ABC transporter ATP-binding protein -
  DQL78_RS11230 (NCTC12421_02301) - 2225139..2225873 (+) 735 WP_016250664.1 ABC transporter permease -
  DQL78_RS11235 (NCTC12421_02302) - 2225866..2226426 (+) 561 WP_016250663.1 hypothetical protein -
  DQL78_RS11240 (NCTC12421_02303) pepF 2226669..2228486 (-) 1818 WP_016250662.1 oligoendopeptidase F Regulator
  DQL78_RS11245 (NCTC12421_02304) - 2228528..2229526 (-) 999 WP_016250661.1 competence protein CoiA -
  DQL78_RS11250 (NCTC12421_02305) ispE 2229602..2230453 (-) 852 WP_016250660.1 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase -
  DQL78_RS12430 (NCTC12421_02306) - 2230516..2230683 (-) 168 WP_016250659.1 hypothetical protein -
  DQL78_RS12695 (NCTC12421_02307) - 2230727..2231026 (-) 300 WP_080637640.1 ATP-binding cassette domain-containing protein -
  DQL78_RS11255 (NCTC12421_02308) - 2231038..2232300 (-) 1263 WP_016250657.1 ABC transporter ATP-binding protein -
  DQL78_RS11260 (NCTC12421_02309) - 2232390..2233262 (-) 873 WP_016250656.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 605 a.a.        Molecular weight: 69321.76 Da        Isoelectric Point: 4.7048

>NTDB_id=1135746 DQL78_RS11240 WP_016250662.1 2226669..2228486(-) (pepF) [Enterococcus cecorum strain NCTC12421]
MSETKQLPLRSEVPEELTWDLSVIFKDDAAFEEAFAALNDRLAEVGNYQGTLANGAKAFLAALEYCLDVMRQLETLYVYS
HLRNDQDTTNATDQALHSRANALVAKASEAIAWFEPEVLSLEDAKIWGYFDELPELSLYRHYIQQIVDNREHILPAEQEA
LLAGAGEIFGAAADTFSVLNNADLEFPVIEDEKGEKVQLSHGVYGQLLESTDRRVRKDAFEGLYKVYQQFARTFASTLST
NVKRHNYAAKVRHFESARQAALSGNHIPESVYETLVSVVNENLPLLHRYMALRKRLLNLDEMHMYDVYTPLLGESSLKYT
YEEATKEAFKALEPMGEEYLAVVKEAFENRWIDVVENKGKRSGAYSSGCYDTNPYILLNWHDTLDQLFTLVHEMGHSVHS
YFTRKNQPYVYGDYSIFLAEIASTTNENILTEYLLETQKDPKVRAFVLNHYLDGFKATVFRQTQFAEFEHFIHVEDAKGT
PLTAEFLNDYYGNLNKRYYGDAVTSDPQISYEWSRIPHFYYNYYVYQYATGFSAASALAKKILSKEENALENYLNYLKAG
NSDYPIEVMKKAGVDMTKADYLKEAMQVFAQRLDELEALVSELEK

Nucleotide


Download         Length: 1818 bp        

>NTDB_id=1135746 DQL78_RS11240 WP_016250662.1 2226669..2228486(-) (pepF) [Enterococcus cecorum strain NCTC12421]
ATGTCAGAAACAAAACAATTACCATTACGTTCTGAAGTACCAGAAGAATTAACTTGGGACTTATCTGTCATTTTTAAAGA
CGATGCAGCCTTTGAAGAAGCATTTGCCGCATTGAATGATCGTTTGGCAGAAGTAGGCAACTATCAAGGAACACTAGCCA
ATGGTGCCAAAGCCTTTTTAGCTGCTTTAGAATATTGCTTAGATGTGATGCGTCAATTAGAAACGCTTTATGTTTATTCT
CATTTACGCAATGACCAAGACACTACCAATGCGACAGATCAAGCCTTGCATTCACGTGCCAATGCCTTAGTTGCTAAAGC
TAGTGAAGCCATTGCCTGGTTTGAACCGGAAGTATTGTCTTTAGAGGATGCAAAAATTTGGGGTTATTTCGATGAATTAC
CAGAATTAAGTCTTTATCGCCATTATATCCAACAAATCGTGGACAATCGCGAACACATTTTACCAGCTGAGCAAGAAGCA
TTATTAGCTGGTGCCGGTGAAATTTTTGGCGCTGCAGCAGATACTTTCTCTGTTTTAAACAATGCTGACCTAGAATTTCC
GGTGATTGAAGATGAAAAAGGCGAAAAAGTCCAATTATCTCATGGCGTATATGGTCAATTATTAGAAAGCACTGATCGTC
GTGTACGTAAAGATGCCTTTGAAGGTTTATATAAAGTGTACCAACAATTTGCGCGTACCTTTGCATCCACTTTAAGTACC
AATGTGAAACGCCATAACTATGCTGCAAAAGTACGTCATTTTGAATCTGCCCGTCAAGCAGCATTAAGTGGCAATCATAT
TCCTGAAAGTGTGTACGAAACTTTAGTCAGCGTGGTTAATGAAAACTTACCATTGTTACACCGCTACATGGCTTTGCGCA
AACGTTTATTAAACTTAGATGAAATGCACATGTACGATGTCTACACACCACTTTTAGGTGAAAGTTCATTGAAATATACT
TATGAAGAAGCCACCAAAGAAGCCTTCAAAGCATTAGAACCAATGGGCGAGGAATACTTAGCTGTGGTGAAAGAAGCTTT
TGAAAACCGCTGGATTGATGTGGTGGAAAATAAAGGTAAACGCAGTGGGGCTTATTCATCAGGTTGCTATGATACCAATC
CATACATCTTGTTAAACTGGCATGACACCCTAGACCAATTATTTACTTTGGTTCATGAAATGGGCCACTCTGTTCATAGT
TACTTCACACGCAAAAATCAACCATATGTATACGGTGATTACTCGATTTTCTTAGCTGAAATTGCGTCTACAACGAATGA
AAATATCTTAACTGAATATTTATTAGAAACACAAAAAGATCCTAAAGTGCGTGCCTTTGTCTTAAATCATTATCTAGATG
GCTTTAAGGCAACTGTTTTCCGTCAAACCCAATTTGCAGAATTTGAACACTTTATTCATGTGGAAGATGCAAAAGGTACC
CCATTAACTGCTGAATTCTTAAATGATTATTATGGCAACTTGAACAAACGCTACTATGGCGATGCAGTAACAAGTGATCC
ACAAATCAGCTATGAATGGTCACGTATCCCTCACTTCTACTACAATTATTATGTTTATCAATATGCAACTGGCTTTAGTG
CTGCCTCTGCCTTAGCGAAGAAGATTCTAAGCAAGGAAGAAAATGCCTTAGAAAACTACTTGAACTATCTAAAAGCTGGT
AATAGTGACTACCCAATCGAAGTCATGAAAAAAGCCGGCGTAGATATGACTAAAGCAGATTATCTAAAAGAAGCCATGCA
AGTCTTCGCACAACGCCTAGACGAACTAGAAGCACTAGTAAGTGAGCTAGAAAAGTAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(117-186)

Peptidase family M3 (Peptidase_M3)

(207-587)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

56.853

97.686

0.555

Multiple sequence alignment