Detailed information NTG1135620

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: DQL80_RS13640
• Genome accession: NZ_LS483302
• Coordinates: 2651434..2652321 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143414.1
• Uniprot ID: A0A6B0AX73
• Organism: Staphylococcus aureus strain NCTC8726
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2646434..2657321

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL80_RS13605	-	2646441..2646529 (+)	89	Protein_2540	hypothetical protein	-
DQL80_RS13610 (NCTC8726_02560)	-	2646637..2647134 (-)	498	WP_001065267.1	glutathione peroxidase	-
DQL80_RS13615	-	2647144..2647404 (-)	261	WP_072468805.1	hypothetical protein	-
DQL80_RS13625	-	2647786..2647899 (-)	114	WP_111680673.1	hypothetical protein	-
DQL80_RS13630 (NCTC8726_02561)	-	2648574..2650574 (-)	2001	WP_111680674.1	ABC transporter permease	-
DQL80_RS13635 (NCTC8726_02562)	-	2650571..2651326 (-)	756	WP_000923762.1	ABC transporter ATP-binding protein	-
DQL80_RS13640 (NCTC8726_02563)	braS	2651434..2652321 (-)	888	WP_000143414.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
DQL80_RS13645	nsaR	2652332..2652998 (-)	667	Protein_2547	nisin susceptibility-associated two-component system response regulator NsaR	-
DQL80_RS13650 (NCTC8726_02566)	-	2653024..2653224 (-)	201	WP_000604724.1	hypothetical protein	-
DQL80_RS13655 (NCTC8726_02567)	-	2653422..2654846 (+)	1425	WP_000953745.1	alkaline phosphatase	-
DQL80_RS14345 (NCTC8726_02568)	-	2654906..2655007 (-)	102	WP_000731972.1	SE2200 family small protein	-
DQL80_RS13665 (NCTC8726_02569)	-	2655129..2655584 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
DQL80_RS13670 (NCTC8726_02570)	-	2655824..2656585 (-)	762	WP_000323450.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34073.33 Da
• Isoelectric Point: 5.6141

>NTDB_id=1135620 DQL80_RS13640 WP_000143414.1 2651434..2652321(-) (braS) [Staphylococcus aureus strain NCTC8726]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKDDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSTGIGLFIVKQISNHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1135620 DQL80_RS13640 WP_000143414.1 2651434..2652321(-) (braS) [Staphylococcus aureus strain NCTC8726]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAGATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCGAATGTTGTGAATCGTGTTCGTCAAGAGGTAATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGT
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCTAATCAATTATACGTAAAAGATAATGGAATCGGTATTAGTGAGGCAGACTTACCTAAA
ATATTCGACAAAGGTTATTCGGGGTATAATGGACAACGTCAAAGTAATTCAACTGGGATTGGCTTATTTATTGTAAAGCA
AATTTCAAATCACACTAATCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A6B0AX73

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.305	100	0.983