Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DQL80_RS10430 Genome accession   NZ_LS483302
Coordinates   2039136..2039852 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain NCTC8726     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2034136..2044852
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL80_RS10400 (NCTC8726_01965) - 2034353..2034979 (+) 627 WP_053875639.1 nitroreductase family protein -
  DQL80_RS10405 (NCTC8726_01966) - 2035339..2036124 (+) 786 WP_111680475.1 carbon-nitrogen family hydrolase -
  DQL80_RS14325 hld 2036724..2036804 (-) 81 WP_000046022.1 delta-hemolysin -
  DQL80_RS10415 (NCTC8726_01968) agrB 2037094..2037663 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  DQL80_RS10420 (NCTC8726_01969) agrD 2037660..2037800 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  DQL80_RS10425 (NCTC8726_01970) agrC 2037825..2039117 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  DQL80_RS10430 (NCTC8726_01971) agrA 2039136..2039852 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  DQL80_RS10435 - 2039924..2040031 (+) 108 WP_031785433.1 hypothetical protein -
  DQL80_RS10440 (NCTC8726_01972) - 2040221..2041180 (-) 960 WP_111680476.1 carbohydrate kinase family protein -
  DQL80_RS10445 (NCTC8726_01973) - 2041177..2042661 (-) 1485 WP_000141419.1 sucrose-6-phosphate hydrolase -
  DQL80_RS10450 (NCTC8726_01974) - 2042810..2043760 (-) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1135616 DQL80_RS10430 WP_000688492.1 2039136..2039852(+) (agrA) [Staphylococcus aureus strain NCTC8726]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1135616 DQL80_RS10430 WP_000688492.1 2039136..2039852(+) (agrA) [Staphylococcus aureus strain NCTC8726]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment