Detailed information NTG1135578

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: DQL88_RS15130
• Genome accession: NZ_LS483301
• Coordinates: 2831755..2832642 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain NCTC13394
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2826755..2837642

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL88_RS15095	-	2826774..2826866 (+)	93	WP_010956583.1	hypothetical protein	-
DQL88_RS15100 (NCTC13394_02775)	-	2826974..2827471 (-)	498	WP_001065268.1	glutathione peroxidase	-
DQL88_RS15105	-	2827481..2827741 (-)	261	WP_001789910.1	hypothetical protein	-
DQL88_RS15115	-	2828123..2828236 (-)	114	WP_011447078.1	hypothetical protein	-
DQL88_RS15120 (NCTC13394_02776)	-	2828895..2830895 (-)	2001	WP_000776751.1	ABC transporter permease	-
DQL88_RS15125 (NCTC13394_02777)	-	2830892..2831647 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
DQL88_RS15130 (NCTC13394_02778)	braS	2831755..2832642 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
DQL88_RS15135 (NCTC13394_02779)	braR	2832653..2833318 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
DQL88_RS15140 (NCTC13394_02780)	-	2833344..2833544 (-)	201	WP_000604728.1	hypothetical protein	-
DQL88_RS15145 (NCTC13394_02781)	-	2833742..2835166 (+)	1425	WP_000953744.1	alkaline phosphatase	-
DQL88_RS15940 (NCTC13394_02782)	-	2835226..2835327 (-)	102	WP_000731972.1	SE2200 family small protein	-
DQL88_RS15155 (NCTC13394_02783)	-	2835449..2835904 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
DQL88_RS15160 (NCTC13394_02784)	-	2836149..2836910 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1135578 DQL88_RS15130 WP_000143419.1 2831755..2832642(-) (braS) [Staphylococcus aureus strain NCTC13394]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1135578 DQL88_RS15130 WP_000143419.1 2831755..2832642(-) (braS) [Staphylococcus aureus strain NCTC13394]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997