Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DQL62_RS10355 Genome accession   NZ_LS483300
Coordinates   2008368..2009084 (+) Length   238 a.a.
NCBI ID   WP_000688496.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NCTC7485     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2003368..2014084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL62_RS10325 (NCTC7485_01959) - 2003570..2004196 (+) 627 WP_111725128.1 nitroreductase family protein -
  DQL62_RS10330 (NCTC7485_01960) - 2004574..2005359 (+) 786 WP_000867955.1 carbon-nitrogen family hydrolase -
  DQL62_RS10335 hld 2005956..2006036 (-) 81 WP_000046022.1 delta-hemolysin -
  DQL62_RS10340 (NCTC7485_01962) - 2006327..2006890 (+) 564 WP_001105699.1 accessory gene regulator AgrB -
  DQL62_RS10345 (NCTC7485_01963) agrD 2006893..2007036 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  DQL62_RS10350 (NCTC7485_01964) agrC 2007066..2008349 (+) 1284 WP_011382329.1 quorum-sensing sensor histidine kinase AgrC -
  DQL62_RS10355 (NCTC7485_01965) agrA 2008368..2009084 (+) 717 WP_000688496.1 quorum-sensing response regulator AgrA Regulator
  DQL62_RS10360 - 2009156..2009263 (+) 108 WP_042852791.1 hypothetical protein -
  DQL62_RS10365 (NCTC7485_01966) - 2009451..2010410 (-) 960 WP_001253290.1 carbohydrate kinase family protein -
  DQL62_RS10370 (NCTC7485_01967) - 2010407..2011891 (-) 1485 WP_000141425.1 sucrose-6-phosphate hydrolase -
  DQL62_RS10375 (NCTC7485_01968) - 2012040..2012990 (-) 951 WP_000790315.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27924.95 Da        Isoelectric Point: 6.1602

>NTDB_id=1135531 DQL62_RS10355 WP_000688496.1 2008368..2009084(+) (agrA) [Staphylococcus aureus strain NCTC7485]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKERCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1135531 DQL62_RS10355 WP_000688496.1 2008368..2009084(+) (agrA) [Staphylococcus aureus strain NCTC7485]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAACATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACGCTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment