Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   JM183_RS04005 Genome accession   NZ_LR962863
Coordinates   887102..887818 (-) Length   238 a.a.
NCBI ID   WP_126496535.1    Uniprot ID   -
Organism   Staphylococcus schleiferi strain NCTC12218     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 882102..892818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JM183_RS03985 (NCTC12218_00849) - 882265..883347 (+) 1083 WP_126496190.1 YeeE/YedE family protein -
  JM183_RS03990 (NCTC12218_00850) - 883372..883596 (+) 225 WP_016425578.1 sulfurtransferase TusA family protein -
  JM183_RS03995 (NCTC12218_00851) - 883964..885163 (+) 1200 WP_281182775.1 IS110 family transposase -
  JM183_RS04000 (NCTC12218_00852) - 885556..887043 (+) 1488 WP_126496534.1 sucrose-6-phosphate hydrolase -
  JM183_RS04005 (NCTC12218_00853) agrA 887102..887818 (-) 717 WP_126496535.1 quorum-sensing response regulator AgrA Regulator
  JM183_RS12300 (NCTC12218_00854) agrC 887833..889125 (-) 1293 WP_126496536.1 quorum-sensing sensor histidine kinase AgrC -
  JM183_RS04015 (NCTC12218_00855) agrD 889149..889286 (-) 138 WP_016425574.1 cyclic lactone autoinducer peptide AgrD -
  JM183_RS04020 (NCTC12218_00856) - 889289..889855 (-) 567 WP_016425573.1 accessory gene regulator AgrB -
  JM183_RS12305 - 890262..890342 (+) 81 WP_154840309.1 delta-lysin family phenol-soluble modulin -
  JM183_RS04025 (NCTC12218_00857) - 890585..891388 (-) 804 WP_016425572.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27958.01 Da        Isoelectric Point: 4.9797

>NTDB_id=1134900 JM183_RS04005 WP_126496535.1 887102..887818(-) (agrA) [Staphylococcus schleiferi strain NCTC12218]
MKILICEDDPKQRERMVSIIENYIMIEEKPMEIEIATDNPYEVLEASKNMSDIGCYFLDIQLESDINGIKLGSEIRKHDP
VGNIIFVTSHTELTYLTFVYKVAAMDFIFKDDPEELRTRIVDCLETALKRLDLLTKDKTVETLELKRGSNSVYVQYDDVM
FFESSPKSHRLIAHLDNRQIEFYGNLKELAQIDDRFFRCHNSFVLNRHNISSVDSKERIAYFKNEEFCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1134900 JM183_RS04005 WP_126496535.1 887102..887818(-) (agrA) [Staphylococcus schleiferi strain NCTC12218]
ATGAAAATATTGATTTGTGAAGACGATCCAAAACAACGTGAGCGCATGGTATCCATTATTGAGAACTATATCATGATTGA
AGAAAAACCTATGGAAATCGAAATTGCTACAGATAATCCATATGAAGTGTTAGAAGCTTCTAAAAACATGAGTGATATTG
GCTGTTATTTTCTAGATATCCAATTAGAATCTGATATTAACGGGATTAAACTCGGAAGTGAGATTCGTAAGCATGACCCT
GTTGGTAATATCATTTTTGTAACAAGCCATACAGAATTGACTTATTTGACATTTGTGTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGACGATCCTGAAGAATTACGTACACGAATTGTTGATTGTTTAGAAACTGCATTAAAACGCTTAGATTTAT
TAACGAAAGATAAAACTGTTGAAACGTTAGAACTGAAACGCGGCAGCAATTCTGTTTATGTTCAATATGATGATGTGATG
TTTTTTGAATCATCACCTAAATCACATCGTTTGATTGCACATTTAGATAATCGTCAAATTGAATTTTATGGCAATCTTAA
AGAATTAGCGCAAATTGATGATCGCTTTTTTAGATGTCATAATAGTTTTGTACTCAACAGACATAACATAAGTAGTGTAG
ATTCTAAAGAACGCATTGCATATTTTAAAAATGAAGAGTTTTGTTATGTTTCAGTACGTAATTTAAAGAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

86.134

100

0.861

Multiple sequence alignment