Detailed information NTG0113396

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: NI25_RS18060
• Genome accession: NZ_CP009754
• Coordinates: 4115392..4117989 (-)
• Length: 865 a.a.
• NCBI ID: WP_061443435.1
• Uniprot ID: -
• Organism: Streptomyces sp. CCM_MD2014
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4110392..4122989

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NI25_RS18040 (NI25_17950)	-	4111988..4112524 (-)	537	WP_061443433.1	DUF2617 family protein	-
NI25_RS39715	-	4112925..4113218 (-)	294	WP_267886335.1	hypothetical protein	-
NI25_RS18050 (NI25_17955)	-	4113411..4114601 (+)	1191	WP_061446970.1	pyridoxal phosphate-dependent aminotransferase	-
NI25_RS18055 (NI25_17960)	-	4114684..4115220 (-)	537	WP_061443434.1	YbjN domain-containing protein	-
NI25_RS18060 (NI25_17965)	clpC	4115392..4117989 (-)	2598	WP_061443435.1	ATP-dependent chaperone ClpB	Regulator
NI25_RS18065 (NI25_17970)	-	4118279..4118614 (-)	336	WP_061443436.1	hypothetical protein	-
NI25_RS18075 (NI25_17980)	-	4118900..4119937 (+)	1038	WP_107071764.1	helix-turn-helix transcriptional regulator	-
NI25_RS18080 (NI25_17985)	-	4119934..4120926 (+)	993	WP_061443438.1	helix-turn-helix transcriptional regulator	-
NI25_RS18085 (NI25_17990)	-	4120923..4121903 (+)	981	WP_061443439.1	helix-turn-helix transcriptional regulator	-
NI25_RS18090 (NI25_17995)	-	4121866..4122903 (-)	1038	WP_061443440.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 865 a.a.
• Molecular weight: 94449.80 Da
• Isoelectric Point: 4.6783

>NTDB_id=113396 NI25_RS18060 WP_061443435.1 4115392..4117989(-) (clpC) [Streptomyces sp. CCM_MD2014]
MDAELTNRSRDAINAASNRAVTEGNADLTPAHLLLALLQGQDNENITDLLAAVEADLAAVRSGAERIVGGLPSVTGSTVA
PPQPNREMLAVVADAQARAKELGDEYLSTEHLLLGIAAKGGAASEVLEGQGASAKKLQEAFRKARGGRRVTTPDPEGQYK
ALEKFGTDLTAAARDGKLDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVPESLKDKRLVA
LDLGAMVAGAKYRGEFEERLKTVLAEIKDSDGQVVTFIDELHTVVGAGAGGDSAMDAGNMLKPMLARGELRMVGATTLDE
YRERIEKDPALERRFQQVLVAEPTVEDSIAILRGLKGRYEAHHKVQIADSALVAAASLSDRYITSRFLPDKAIDLVDEAA
SRLRMEIDSSPVEIDELQRAVDRLKMEELAIGKETDAASLERLERLRRDLADKEEELRGLNARWEKEKQSLNRVGELKEK
LDELRGQAERAQRDGDFDTASKLLYGEIPTLERDLEAASEAEEEVARDTMVKEEVGADDIADVVASWTGIPAGRLMEGET
QKLLRMEDELGKRLIGQTEAVRAVSDAVRRSRAGIADPDRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMVRIDMSE
YSEKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYTVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTILVL
TSNLGSQYLVDPTTGEAEKKEQVLEVVRASFKPEFLNRLDDLVVFSALSKEELSRIARLQINGLARRLAERRLTLEVTDE
ALAWLAEEGNDPAYGARPLRRLVQTAIGDRLAREILAGEIKDGDTVRVDRFGDDLIVGPASGKTL

Nucleotide

• Length: 2598 bp

>NTDB_id=113396 NI25_RS18060 WP_061443435.1 4115392..4117989(-) (clpC) [Streptomyces sp. CCM_MD2014]
GTGGACGCCGAGCTGACCAACCGGAGCCGGGACGCGATCAACGCGGCCAGCAACCGGGCCGTGACCGAGGGAAACGCCGA
CCTCACCCCCGCCCACCTGCTCCTTGCGCTGCTCCAGGGGCAGGACAACGAGAACATCACCGACCTGCTCGCCGCCGTCG
AGGCCGACCTCGCCGCCGTACGCTCCGGCGCCGAGCGCATCGTCGGCGGGCTGCCCAGCGTGACCGGGTCCACCGTCGCA
CCCCCGCAGCCCAACCGTGAGATGCTCGCCGTGGTCGCCGACGCCCAGGCCCGCGCCAAGGAACTCGGGGACGAGTACCT
CTCCACCGAGCACCTGCTCCTCGGCATCGCCGCGAAGGGCGGCGCGGCCAGTGAGGTACTGGAGGGGCAGGGAGCGAGTG
CCAAGAAGCTGCAGGAGGCCTTCCGCAAGGCGAGGGGAGGGCGCCGCGTGACCACTCCCGACCCCGAGGGCCAGTACAAG
GCCCTGGAGAAGTTCGGCACCGACCTCACCGCCGCCGCCCGGGACGGCAAGCTCGACCCCGTCATCGGCCGCGACCAGGA
GATCCGCCGCGTCGTGCAGGTGCTGAGCCGGCGGACCAAGAACAACCCCGTGCTCATCGGCGAACCCGGCGTCGGCAAGA
CGGCCGTCGTCGAAGGGCTCGCCCAGCGGATCGTCAAGGGGGACGTGCCCGAGTCGCTGAAGGACAAGCGGCTGGTGGCG
CTGGACCTCGGGGCCATGGTCGCCGGGGCCAAGTACCGGGGCGAGTTCGAGGAGCGGCTCAAGACCGTCCTCGCCGAGAT
CAAGGACTCCGACGGGCAGGTCGTCACCTTCATCGACGAGCTGCACACCGTCGTCGGCGCCGGCGCCGGCGGGGACTCCG
CCATGGACGCCGGGAACATGCTCAAGCCCATGCTGGCCCGCGGCGAGCTGCGCATGGTGGGTGCCACGACGCTCGACGAG
TACCGGGAGCGGATCGAGAAGGACCCCGCCCTGGAGCGCCGCTTCCAGCAGGTGCTGGTCGCCGAGCCGACCGTCGAGGA
CTCCATCGCGATCCTGCGCGGACTCAAGGGGCGGTACGAGGCGCACCACAAGGTGCAGATCGCGGACAGCGCGCTGGTGG
CCGCCGCGAGCCTCTCCGACCGCTACATCACCTCCCGTTTCCTGCCCGACAAGGCCATCGACCTCGTCGACGAGGCCGCC
TCCCGGCTGCGCATGGAGATCGACTCCTCGCCCGTCGAGATCGACGAACTCCAGCGCGCCGTCGACCGGCTGAAGATGGA
GGAGCTGGCGATCGGCAAGGAGACCGACGCCGCCTCCCTCGAACGCCTGGAGCGGCTGCGCCGCGACCTCGCCGACAAGG
AGGAGGAGCTGCGCGGCCTCAACGCCCGCTGGGAGAAGGAGAAGCAGTCCCTCAACCGGGTCGGCGAGCTGAAGGAGAAG
CTCGACGAACTGCGCGGGCAGGCCGAGCGCGCCCAGCGCGACGGCGACTTCGACACCGCCAGCAAGCTGCTCTACGGCGA
GATCCCGACGCTGGAGCGGGACCTGGAGGCCGCCTCCGAGGCGGAGGAAGAAGTCGCCCGGGACACCATGGTCAAGGAGG
AGGTCGGCGCCGACGACATCGCCGACGTCGTCGCCTCCTGGACCGGCATCCCCGCAGGGCGCCTCATGGAGGGCGAGACG
CAGAAGCTGCTGCGCATGGAGGACGAGCTGGGCAAGCGGCTCATCGGGCAGACCGAGGCCGTACGGGCCGTCTCCGACGC
CGTACGGCGCTCCCGGGCCGGGATCGCCGACCCGGACCGCCCGACCGGTTCGTTCCTCTTCCTCGGCCCCACCGGTGTCG
GCAAGACCGAGCTGGCCAAGGCGCTCGCCGACTTCCTCTTCGACGACGAGCGGGCCATGGTCCGCATCGACATGAGCGAG
TACAGCGAGAAGCACAGCGTGGCCCGGCTGGTCGGCGCCCCGCCCGGATACGTCGGGTACGAGGAGGGCGGCCAGCTCAC
CGAGGCGGTGCGGCGGCGGCCCTACACCGTCGTGCTGCTCGACGAGGTGGAGAAGGCGCACCCCGAGGTCTTCGACATCC
TGCTCCAGGTGCTCGACGACGGCCGCCTCACCGACGGCCAGGGCCGCACCGTCGACTTCCGCAACACCATCCTGGTGCTC
ACCTCCAACCTGGGCAGCCAGTACCTGGTCGACCCGACCACCGGCGAGGCGGAGAAGAAGGAGCAGGTCCTGGAGGTGGT
GCGGGCCTCCTTCAAGCCGGAGTTCCTCAACCGGCTCGACGACCTGGTGGTCTTCTCGGCGCTCAGCAAGGAAGAGCTGA
GCCGCATCGCACGGCTGCAGATCAACGGCCTGGCCCGGCGCCTCGCCGAACGCCGCCTCACCCTGGAGGTCACCGACGAG
GCCCTCGCCTGGCTGGCGGAGGAGGGCAACGACCCGGCCTACGGCGCCCGCCCGCTGCGCCGCCTCGTCCAGACCGCGAT
CGGCGACCGGCTCGCCCGCGAGATCCTCGCCGGCGAGATCAAGGACGGCGACACGGTCCGCGTGGACCGCTTCGGCGACG
ACCTGATCGTGGGCCCCGCGAGCGGCAAGACGCTGTAG

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (344-446)

• AAA domain (Cdc48 subfamily) (AAA_2) (600-761)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-338)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-146)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (768-848)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	43.584	100	0.436
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.75	90.636	0.397
clpC	Lactococcus lactis subsp. cremoris KW2	45.938	82.543	0.379