Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   SAGV69_RS11840 Genome accession   NZ_CP009681
Coordinates   2267614..2268321 (+) Length   235 a.a.
NCBI ID   WP_000094093.1    Uniprot ID   A0A1D4DWM6
Organism   Staphylococcus aureus strain Gv69     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2262614..2273321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAGV69_RS11780 (SAGV69_02417) - 2262791..2263414 (-) 624 WP_000139720.1 DUF1071 domain-containing protein -
  SAGV69_RS11785 (SAGV69_03958) - 2263407..2263628 (-) 222 WP_000815401.1 DUF2483 family protein -
  SAGV69_RS11790 (SAGV69_02419) - 2263638..2263898 (-) 261 WP_000291489.1 DUF1108 family protein -
  SAGV69_RS11795 - 2263991..2264152 (-) 162 WP_000066020.1 DUF1270 domain-containing protein -
  SAGV69_RS11800 (SAGV69_02420) - 2264149..2264469 (-) 321 WP_001120197.1 DUF771 domain-containing protein -
  SAGV69_RS11805 (SAGV69_02421) - 2264528..2265160 (+) 633 WP_000275058.1 hypothetical protein -
  SAGV69_RS11810 - 2265175..2265315 (-) 141 WP_000939496.1 hypothetical protein -
  SAGV69_RS11815 (SAGV69_02422) - 2265346..2265543 (-) 198 WP_001148861.1 hypothetical protein -
  SAGV69_RS11820 (SAGV69_02423) - 2265559..2266311 (-) 753 WP_001148617.1 phage antirepressor KilAC domain-containing protein -
  SAGV69_RS11825 (SAGV69_02424) - 2266368..2266907 (+) 540 WP_000351243.1 hypothetical protein -
  SAGV69_RS11830 (SAGV69_02425) - 2266931..2267191 (-) 261 WP_000435341.1 transcriptional regulator -
  SAGV69_RS11835 (SAGV69_02426) - 2267204..2267443 (-) 240 WP_000548578.1 helix-turn-helix transcriptional regulator -
  SAGV69_RS11840 (SAGV69_02427) irvR 2267614..2268321 (+) 708 WP_000094093.1 XRE family transcriptional regulator Regulator
  SAGV69_RS17270 (SAGV69_02428) - 2268333..2268488 (+) 156 WP_001049399.1 hypothetical protein -
  SAGV69_RS11845 (SAGV69_02429) - 2268475..2268660 (+) 186 WP_001089804.1 hypothetical protein -
  SAGV69_RS11850 (SAGV69_02430) - 2268860..2269026 (+) 167 Protein_2267 hypothetical protein -
  SAGV69_RS11855 (SAGV69_02431) - 2269166..2269705 (+) 540 WP_000391618.1 type II toxin-antitoxin system PemK/MazF family toxin -
  SAGV69_RS11860 (SAGV69_02432) - 2269878..2270914 (+) 1037 Protein_2269 tyrosine-type recombinase/integrase -
  SAGV69_RS11865 (SAGV69_04251) sph 2270968..2271796 (+) 829 Protein_2270 sphingomyelin phosphodiesterase -
  SAGV69_RS11870 (SAGV69_02435) lukG 2272034..2273050 (-) 1017 WP_000595324.1 bi-component leukocidin LukGH subunit G -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26769.35 Da        Isoelectric Point: 5.4082

>NTDB_id=113255 SAGV69_RS11840 WP_000094093.1 2267614..2268321(+) (irvR) [Staphylococcus aureus strain Gv69]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=113255 SAGV69_RS11840 WP_000094093.1 2267614..2268321(+) (irvR) [Staphylococcus aureus strain Gv69]
ATGAGTTCATTTTCTTCGAATTTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTTAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTATCATCT
CAACTCACGCCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(123-234)

Helix-turn-helix (HTH_3)

(8-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1D4DWM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

30.769

100

0.374

Multiple sequence alignment