Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   BKMNNEJI_RS14765 Genome accession   NZ_LR822061
Coordinates   2934560..2935276 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus isolate HU-14     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2929560..2940276
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKMNNEJI_RS14745 (LJDFIFNA_02828) - 2930652..2931602 (+) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -
  BKMNNEJI_RS14750 (LJDFIFNA_02829) - 2931751..2933235 (+) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  BKMNNEJI_RS14755 (LJDFIFNA_02830) - 2933232..2934191 (+) 960 WP_031879505.1 carbohydrate kinase family protein -
  BKMNNEJI_RS14760 (LJDFIFNA_RS14760) - 2934379..2934488 (-) 110 Protein_2883 hypothetical protein -
  BKMNNEJI_RS14765 (LJDFIFNA_02831) agrA 2934560..2935276 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  BKMNNEJI_RS14770 (LJDFIFNA_02832) agrC 2935295..2936185 (-) 891 Protein_2885 quorum-sensing sensor histidine kinase AgrC -
  BKMNNEJI_RS14775 (LJDFIFNA_02833) - 2936284..2937456 (-) 1173 WP_000195429.1 IS256-like element IS256 family transposase -
  BKMNNEJI_RS14780 (LJDFIFNA_RS14780) - 2937560..2937910 (-) 351 Protein_2887 sensor histidine kinase AgrC -
  BKMNNEJI_RS14785 (LJDFIFNA_02835) agrD 2937940..2938083 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  BKMNNEJI_RS14790 (LJDFIFNA_02836) - 2938086..2938649 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  BKMNNEJI_RS15370 hld 2938939..2939019 (+) 81 WP_000046022.1 delta-hemolysin -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1132300 BKMNNEJI_RS14765 WP_000688492.1 2934560..2935276(-) (agrA) [Staphylococcus aureus isolate HU-14]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1132300 BKMNNEJI_RS14765 WP_000688492.1 2934560..2935276(-) (agrA) [Staphylococcus aureus isolate HU-14]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment