Detailed information NTG1132295

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: BKMNNEJI_RS11210
• Genome accession: NZ_LR822061
• Coordinates: 2254652..2255539 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus isolate HU-14
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2249652..2260539

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BKMNNEJI_RS11180 (LJDFIFNA_02145)	-	2250384..2251145 (+)	762	WP_000323441.1	alpha/beta hydrolase	-
BKMNNEJI_RS11185 (LJDFIFNA_02146)	-	2251390..2251845 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
BKMNNEJI_RS15260 (LJDFIFNA_02147)	-	2251967..2252068 (+)	102	WP_000731976.1	SE2200 family small protein	-
BKMNNEJI_RS11195 (LJDFIFNA_02148)	-	2252128..2253552 (-)	1425	WP_000953755.1	alkaline phosphatase	-
BKMNNEJI_RS11200 (LJDFIFNA_02149)	-	2253750..2253950 (+)	201	WP_000604730.1	hypothetical protein	-
BKMNNEJI_RS11205 (LJDFIFNA_02150)	braR	2253976..2254641 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
BKMNNEJI_RS11210 (LJDFIFNA_02151)	braS	2254652..2255539 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
BKMNNEJI_RS11215 (LJDFIFNA_02152)	-	2255647..2256402 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
BKMNNEJI_RS11220 (LJDFIFNA_02153)	-	2256399..2258399 (+)	2001	WP_000776751.1	ABC transporter permease	-
BKMNNEJI_RS11225 (LJDFIFNA_RS11225)	-	2259058..2259171 (+)	114	Protein_2184	hypothetical protein	-
BKMNNEJI_RS11230 (LJDFIFNA_02154)	-	2259553..2259813 (+)	261	WP_001791974.1	hypothetical protein	-
BKMNNEJI_RS11235 (LJDFIFNA_02155)	-	2259823..2260320 (+)	498	WP_001065268.1	glutathione peroxidase	-
BKMNNEJI_RS11240 (LJDFIFNA_RS11240)	-	2260428..2260520 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1132295 BKMNNEJI_RS11210 WP_000143425.1 2254652..2255539(+) (braS) [Staphylococcus aureus isolate HU-14]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1132295 BKMNNEJI_RS11210 WP_000143425.1 2254652..2255539(+) (braS) [Staphylococcus aureus isolate HU-14]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1