Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LJDFIFNA_RS14785 Genome accession   NZ_LR822060
Coordinates   2933225..2933941 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus isolate P3.1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2928225..2938941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LJDFIFNA_RS14765 (BKMNNEJI_02827) - 2929317..2930267 (+) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -
  LJDFIFNA_RS14770 (BKMNNEJI_02828) - 2930416..2931900 (+) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  LJDFIFNA_RS14775 (BKMNNEJI_02829) - 2931897..2932856 (+) 960 WP_031879505.1 carbohydrate kinase family protein -
  LJDFIFNA_RS14780 (H0509_RS14780) - 2933044..2933153 (-) 110 Protein_2882 hypothetical protein -
  LJDFIFNA_RS14785 (BKMNNEJI_02830) agrA 2933225..2933941 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  LJDFIFNA_RS14790 (BKMNNEJI_02831) agrC 2933960..2934850 (-) 891 Protein_2884 quorum-sensing sensor histidine kinase AgrC -
  LJDFIFNA_RS14795 (BKMNNEJI_02832) - 2934949..2936121 (-) 1173 WP_000195429.1 IS256-like element IS256 family transposase -
  LJDFIFNA_RS14800 (H0509_RS14800) - 2936225..2936575 (-) 351 Protein_2886 sensor histidine kinase AgrC -
  LJDFIFNA_RS14805 (BKMNNEJI_02834) agrD 2936605..2936748 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  LJDFIFNA_RS14810 (BKMNNEJI_02835) - 2936751..2937314 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  LJDFIFNA_RS15390 hld 2937604..2937684 (+) 81 WP_000046022.1 delta-hemolysin -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1132255 LJDFIFNA_RS14785 WP_000688492.1 2933225..2933941(-) (agrA) [Staphylococcus aureus isolate P3.1]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1132255 LJDFIFNA_RS14785 WP_000688492.1 2933225..2933941(-) (agrA) [Staphylococcus aureus isolate P3.1]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment