Detailed information NTG1132002

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H1W80_RS05355
• Genome accession: NZ_LR822040
• Coordinates: 1010905..1011786 (-)
• Length: 293 a.a.
• NCBI ID: WP_087009970.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1125
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1005905..1016786

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W80_RS05330 (STHERMO_1185)	vicR	1006611..1007318 (-)	708	WP_011227274.1	response regulator YycF	Regulator
H1W80_RS05335	-	1007844..1008611 (+)	768	Protein_990	amino acid ABC transporter ATP-binding protein	-
H1W80_RS05340 (STHERMO_1189)	-	1008623..1009456 (+)	834	WP_087009968.1	transporter substrate-binding domain-containing protein	-
H1W80_RS05345 (STHERMO_1190)	-	1009474..1010172 (+)	699	WP_087009969.1	amino acid ABC transporter permease	-
H1W80_RS05350 (STHERMO_1191)	-	1010184..1010834 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
H1W80_RS05355 (STHERMO_1192)	endA	1010905..1011786 (-)	882	WP_087009970.1	DNA/RNA non-specific endonuclease	Machinery gene
H1W80_RS05360 (STHERMO_1193)	-	1011848..1012036 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H1W80_RS05365 (STHERMO_1194)	murA	1012038..1013321 (-)	1284	WP_180473247.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H1W80_RS05370 (STHERMO_1195)	-	1013391..1013627 (-)	237	WP_002946959.1	DUF1146 family protein	-
H1W80_RS05375 (STHERMO_1196)	galE	1013815..1014835 (-)	1021	Protein_998	UDP-glucose 4-epimerase GalE	-
H1W80_RS05380 (STHERMO_1198)	-	1014850..1015158 (-)	309	WP_231906153.1	DUF4832 domain-containing protein	-
H1W80_RS09575 (STHERMO_1199)	-	1015140..1015304 (-)	165	WP_231906154.1	hypothetical protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31757.55 Da
• Isoelectric Point: 10.2316

>NTDB_id=1132002 H1W80_RS05355 WP_087009970.1 1010905..1011786(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1125]
MAKRKTSLKNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDSPIRQVASLVAGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1132002 H1W80_RS05355 WP_087009970.1 1010905..1011786(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1125]
ATGGCAAAAAGAAAGACATCTTTGAAAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAGTCCTATCAGACAAGTAGCAAGCCTAGTTGCAGGTAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594