Detailed information NTG1131888

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: H1W87_RS05475
• Genome accession: NZ_LR822037
• Coordinates: 1033121..1034002 (-)
• Length: 293 a.a.
• NCBI ID: WP_022096754.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1121
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1028121..1039002

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W87_RS05450 (STHERMO_1212)	vicR	1028827..1029534 (-)	708	WP_173940375.1	response regulator YycF	Regulator
H1W87_RS05455 (STHERMO_1214)	-	1030059..1030826 (+)	768	WP_179966655.1	amino acid ABC transporter ATP-binding protein	-
H1W87_RS05460 (STHERMO_1215)	-	1030838..1031671 (+)	834	WP_002953142.1	transporter substrate-binding domain-containing protein	-
H1W87_RS05465 (STHERMO_1216)	-	1031689..1032387 (+)	699	WP_011226087.1	amino acid ABC transporter permease	-
H1W87_RS05470 (STHERMO_1217)	-	1032399..1033049 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
H1W87_RS05475 (STHERMO_1218)	endA	1033121..1034002 (-)	882	WP_022096754.1	DNA/RNA non-specific endonuclease	Machinery gene
H1W87_RS05480 (STHERMO_1219)	-	1034064..1034252 (-)	189	WP_176243147.1	DNA-directed RNA polymerase subunit beta	-
H1W87_RS05485 (STHERMO_1220)	murA	1034254..1035525 (-)	1272	WP_022096753.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
H1W87_RS05490 (STHERMO_1221)	-	1035595..1035831 (-)	237	WP_180478024.1	DUF1146 family protein	-
H1W87_RS05495 (STHERMO_1222)	galE	1036019..1037032 (-)	1014	WP_180478026.1	UDP-glucose 4-epimerase GalE	-
H1W87_RS05500 (STHERMO_1223)	-	1037047..1037502 (-)	456	WP_180478028.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31813.61 Da
• Isoelectric Point: 10.1789

>NTDB_id=1131888 H1W87_RS05475 WP_022096754.1 1033121..1034002(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1121]
MAKRKTSLTNKQKRQLVTLIIAVLIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSINSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=1131888 H1W87_RS05475 WP_022096754.1 1033121..1034002(-) (endA) [Streptococcus thermophilus isolate STH_CIRM_1121]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGTTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAATAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCAACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	70.635	86.007	0.608
endA	Streptococcus pneumoniae D39	70.635	86.007	0.608
endA	Streptococcus pneumoniae R6	70.635	86.007	0.608
endA	Streptococcus pneumoniae TIGR4	70.635	86.007	0.608